In one paragraphArticle in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
21 authors.
Ina A Stelzer *Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9974-4661 Joshua Gillard *Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.
Christopher Urbschat *Department of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-8866-9133 Kristin Thiele *Department of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-9343-9834 Dorien FeyaertsDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-0795-6625 Mirja PagenkemperDepartment of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ann-Christin TallarekDepartment of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bettina HollwitzDepartment of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Masaki SatoDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0001-6724-7786 Edward GanioDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.
Maïgane DiopDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.
Kazuo AndoDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0003-1778-1344 Jakob EinhausDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-3450-4325 Nima AghaeepourDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-6117-8764 David K StevensonDepartment of Pediatrics, Stanford University, Stanford, CA, USA.
Nicola GaglianiHamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0001-8514-1395 Anna WoestemeierDepartment for General, Visceral, Thoracic and Vascular Surgery, University Hospital of Bonn, Bonn, Germany.ORCID 0000-0003-0577-0576 Stefan BonnHamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-4366-5662 Anke DiemertDepartment of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Petra C ArckDepartment of Obstetrics and Prenatal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. p.arck@uke.de.ORCID 0000-0002-2932-926X Brice GaudillièreDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Stanford, CA, USA. gbrice@stanford.edu.ORCID 0000-0002-3475-5706 Funding
Deutsche Forschungsgemeinschaft (German Research Foundation) CRC 1713: 534829736National Institute of Health (NICHD) K99/R00HD105016NIGMS NIH HHS T32-GM007365NIGMS NIH HHS T32-GM145402NIH HHS P01-HD106414
6 · The paper itselfAbstract
The majority of spontaneous preterm births (sPTB) occurs without identifiable clinical indications or apparent risk factors. A dysregulated maternal immune adaptation at delivery has been associated with sPTB. Yet, a precise understanding of maternal immune dynamics preceding sPTB remains lacking. Here we show, in a nested case-control study within a low-risk, population-based pregnancy cohort, that an abnormal immune adaptation in mothers' blood precedes sPTB by weeks to months and discriminates sPTB cases from term controls (AUROC: 0.7). Prominent features include enhanced immune cell responses to an adrenergic stimulus during the first and second trimesters, followed by increased production of pro-inflammatory cytokines in the third trimester in sPTB vs. term pregnancies. Transcriptome analysis of second trimester single-cell CD4
Indexed as
Premature BirthAdaptation, PhysiologicalAdultCase-Control StudiesCD4-Positive T-LymphocytesCytokinesFemaleGene Expression ProfilingHumansPregnancyPregnancy Trimester, SecondRisk FactorsTh17 CellsCytokines
Identifiers
PMID42509242
PMCPMC13408597
What OpenQuestion holds
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LicenceCC BY
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