Evidence map›Paper›PMID 42508005›Full record

ArticleJMIR pediatrics and parenting2026

Evaluating the Picterus Jaundice Pro App for Neonatal Jaundice Screening by Parents: Prospective Mixed Methods Study.

Frouke J Terpstra, Ariela Hazan, Elkana Kohn, Matitiahu Berkovitch, Tjalling W de Vries, Jasper V Been, Peter H Dijk, Christian V Hulzebos

Abstract read
In one paragraph

Article in JMIR pediatrics and parenting, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Frouke J TerpstraDepartment of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0009-0000-6888-6344
Ariela HazanClinical Pharmacology and Toxicology, Gray School of Medicine, Tel Aviv University, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel.ORCID https://orcid.org/0009-0007-6125-2868
Elkana KohnClinical Pharmacology and Toxicology, Gray School of Medicine, Tel Aviv University, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel.ORCID https://orcid.org/0000-0003-0197-4440
Matitiahu BerkovitchClinical Pharmacology and Toxicology, Pediatric Division, Gray School of Medicine, Tel Aviv University, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel.ORCID https://orcid.org/0000-0001-8151-8220
Tjalling W de VriesDepartment of Pediatrics, Frisius Medical Center, Leeuwarden, The Netherlands.ORCID https://orcid.org/0000-0003-0940-1719
Jasper V BeenDivision of Neonatology, Department of Neonatal and Paediatric Intensive Care, Erasmus MC Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-4907-6466
Peter H DijkDepartment of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-1129-648X
Christian V HulzebosDepartment of Neonatology, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-8159-7501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeonatal jaundice is a very common condition in the first week of life requiring timely recognition of the small subset of neonates at risk of developing severe neonatal hyperbilirubinemia (SNH). Total serum bilirubin, as quantified through blood testing, remains the gold standard for diagnosis, whereas screening based on visual inspection has been proven unreliable in identifying which jaundiced neonates require total serum bilirubin. Picterus Jaundice Pro (JP) is a mobile health app developed for use by health care professionals and parents to screen for imminent SNH. However, parental user experiences with Picterus JP remain largely unexplored.

objectiveThis study aimed to evaluate the usability and user-friendliness of Picterus JP when used and evaluated by parents.

methodsBetween August 2023 and January 2025, we conducted a prospective mixed methods study at 3 maternity care settings: the maternity wards of 2 hospitals in the Netherlands and 1 hospital in Israel. Parents were invited to participate if their infant was near term born (gestational age of ≥35 weeks) and at least 12 hours old but still in the first week of life. Parents used Picterus JP once according to the manufacturer's instructions. Immediately afterward, usability was evaluated using the validated mHealth App Usability Questionnaire, an instrument measured on a 7-point Likert scale ranging from 1 ("strongly disagree") to 7 ("strongly agree"), and open-ended questions. A subset of parents and nurses participated in semistructured interviews and focus groups.

resultsIn total, 123 parents completed the questionnaire. The median mHealth App Usability Questionnaire score was 6 (IQR 5-7) out of 7. A total of 87.7% (100/114) of the parents indicated that they would use Picterus JP at home. Parents reported that they found the app easy, quick, and convenient, although 55.8% (67/120) reported a failure on the first try. Some parents struggled to find or interpret the instructions, but most of those who tried again (79/105, 75.2%) obtained a bilirubin estimate. Additionally, 12 nurses from 2 participating maternity wards provided their observations on parents' use of Picterus JP in 2 focus groups. Thematic analysis of all combined data identified 3 themes that were considered important for the usability of Picterus JP: intention to use Picterus JP, infant well-being, and instruction and guidance.

conclusionsParents rated Picterus JP highly in terms of usability despite encountering difficulties during initial use. Technical improvements and more proactive guidance seem important to support successful parental use. Nonetheless, both parents and nurses were positive about the potential of Picterus JP for home screening for SNH.

Indexed as

bilirubin screeningclinical decision supportdigital healthhyperbilirubinemiajaundice detectionmobile healthneonatal jaundice

Identifiers

PMID42508005
PMCPMC13458348

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.