ArticleAnnals of Indian Academy of Neurology2026
Factors Associated with Leptomeningeal Collaterals and Their Impact on Functional Outcomes in Anterior Circulation Acute Ischemic Stroke.
Article in Annals of Indian Academy of Neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesLeptomeningeal collaterals are essential for maintaining cerebral perfusion during acute large vessel occlusion (LVO) and are predictive of favorable outcomes in stroke patients. However, the factors influencing baseline collateral status are not well understood. We aimed to identify factors predicting poor baseline collateral status and unfavorable 3-month outcomes in acute ischemic stroke (AIS) patients with LVO in the anterior circulation in the Indian subcontinent.
methodsWe retrospectively enrolled 239 patients who underwent computed tomography angiography within 24 hours of acute ischemic stroke. Patient demographics, vascular risk factors, baseline stroke severity, etiology, and 3-month functional outcomes were collected.
resultsThe mean age was 59.5 ± 13.5 years; 152 (64%) patients were males, and the median baseline National Institutes of Health Stroke Scale (NIHSS) score was 15. Bivariate analysis showed that male sex (77% vs. 58%, P = 0.004), absence of valvular disease (92% vs. 82%), lower clot burden score (CBS) (32% vs. 16%, P = 0.003), and renal dysfunction (11% vs. 3%, P = 0.01) were associated with poor collateral status. Logistic regression identified renal dysfunction (odds ratio [OR] 3.9; 95% confidence interval [CI], 1.2-14.68; P = 0.031) and lower CBS (OR, 0.40; 95% CI, 0.23-0.93; P = 0.030) as independently associated with poor collateral status. Poor 3-month outcomes were associated with older age (OR, 1.96; 95% CI, 1.05-3.68; P = 0.034), large vessel atherosclerosis (OR, 2.66; 95% CI, 1.27-5.56; P = 0.009), and poor collateral status (OR, 2.35; 95% CI, 1.18-4.66; P = 0.014).
conclusionsLower CBS and renal dysfunction were associated with poor collateral status at baseline in AIS patients with LVO. Advanced age, large vessel atherosclerosis, poor collateral status, and greater stroke severity predicted poor functional outcomes at 3 months.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.