Evidence map›Paper›PMID 42507330›Full record

ArticleJournal of applied clinical medical physics2026

Obese patient imaging: Potential dose reduction with photon-counting CT.

Leening P Liu, Kai Mei, Shobhit Sharma, Steven Ross, Sandra S Halliburton, Richard Thompson, Naruomi Akino, Ali H Dhanaliwala, Leonid Roshkovan, Harold I Litt and 1 more

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Leening P LiuDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kai MeiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Shobhit SharmaCanon Medical Research USA, Vernon Hills, Illinois, USA.
Steven RossCanon Medical Research USA, Vernon Hills, Illinois, USA.
Sandra S HalliburtonCanon Healthcare USA, Cleveland, Ohio, USA.
Richard ThompsonCanon Healthcare USA, Cleveland, Ohio, USA.
Naruomi AkinoCanon Medical Systems Corporation, Otawara, Japan.
Ali H DhanaliwalaDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Leonid RoshkovanDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Harold I LittDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Peter B NoëlDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

PixelPrint: a 3D printing platform for creating lifelike patient-based CT phantomsR01EB035092 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Peter B Noel · 2024 to 2026
$1.8M
Canon Medical Systems Corporation (Otawara, Japan)NIBIB NIH HHS R01 EB035092NIH HHS R01EB035092
6 · The paper itself

Abstract

backgroundPhoton-counting CT (PCCT) offers key advantages over energy integrating detector CT (EID-CT), especially in low-dose scans and imaging larger patients. As obesity rates rise, minimizing image noise is critical for diagnostic accuracy. PURPOSE: To evaluate the dose efficiency of cadmium-zinc-telluride (CZT) based PCCT compared to EID-CT across phantom sizes.

methodsA patient-specific 3D-printed pancreas phantom and a phantom with tissue mimicking inserts were placed in extension rings corresponding to the 50

resultsPCCT demonstrated reduced noise compared to EID-CT across all phantom sizes and doses with average noise reductions of 22%, 23%, 25%, and 28% for the 50

conclusionsPCCT exhibited superior dose efficiency compared to EID-CT across a range of phantom sizes. The enhanced dose efficiency enables both noise reduction and potential dose reduction for the imaging of obese patients and low-dose imaging applications. Further evaluation with task-based image quality metrics remains necessary before clinical implementation of dose reduction.

Indexed as

Image Processing, Computer-AssistedObesityPhantoms, ImagingPhotonsTomography, X-Ray ComputedCadmiumHumansPrinting, Three-DimensionalRadiation DosageTelluriumZincCadmiumCdZnTeTelluriumZincdiagnostic imagingobesityphoton‐counting CTradiation dosage

Identifiers

PMID42507330
PMCPMC13404245

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.