Evidence map›Paper›PMID 42507294›Full record

Observational studyJournal of patient-reported outcomes2026

Higher severity of infant RSV infections is associated with lower parental quality of life - a European observational study.

Ilona Trautmannsberger, Sabina Bösl, Ina Adamek, Christian Apfelbacher, Philippe Beutels, Brigitte Essers, Ulrike Ravens-Sieberer, Catherine Weil-Olivier, Raffaella Nenna, Martin Wetzke and 4 more

Registry-linked trialAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Journal of patient-reported outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05550545 (ResQ Family), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05550545 unknown statusnot on this map

ResQ Family: Impact of Respiratory Syncytial Virus (RSV) Hospitalisation on Quality of Life of Families - A Multi-Country Study

TypeobservationalSponsorGlobal Foundation for the Care of Newborn InfantsRan2022 to 2024Enrolled120ConditionsRSV Infection, Quality of Life, Infant ALL, Caregiver BurdenArmscohort study
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ilona TrautmannsbergerGlobal Foundation for the Care of Newborn Infants (GFCNI), Hofmannstraße 7a, 81378, Munich, Germany.ORCID http://orcid.org/0000-0002-9996-6117
Sabina BöslGlobal Foundation for the Care of Newborn Infants (GFCNI), Hofmannstraße 7a, 81378, Munich, Germany.ORCID http://orcid.org/0000-0002-6011-9332
Ina AdamekGlobal Foundation for the Care of Newborn Infants (GFCNI), Hofmannstraße 7a, 81378, Munich, Germany.ORCID http://orcid.org/0009-0004-9614-1058
Christian ApfelbacherInstitute of Social Medicine and Health Systems Research (ISMHSR), Otto von Guericke University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany.ORCID http://orcid.org/0000-0003-3805-8219
Philippe BeutelsCentre for Health Economics Research & Modelling Infectious Diseases (CHERMID), Vaccine & Infectious Disease Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Campus Drie Eiken - Gebouw S, S241, Universiteitsplein 1, Antwerpen, 2610, Belgium.ORCID http://orcid.org/0000-0001-5034-3595
Brigitte EssersDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, PO Box 5800, Maastricht, 6202 AZ, The Netherlands.
Ulrike Ravens-SiebererDepartment of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0002-2031-095X
Catherine Weil-OlivierPediatrics, University of Paris, Paris, France.ORCID http://orcid.org/0000-0001-5271-1945
Raffaella NennaDepartment of Maternal, Infantile, and Urological Sciences, Sapienza University of Rome, 00161, Rome, Italy.ORCID http://orcid.org/0000-0001-8880-3462
Martin WetzkeClinic for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School (MHH), Carl-Neuberg-Str. 1, D-30625, Hannover, Germany.
Silke MaderGlobal Foundation for the Care of Newborn Infants (GFCNI), Hofmannstraße 7a, 81378, Munich, Germany. S.MaderOffice@gfcni.org.ORCID http://orcid.org/0000-0002-3396-0177
Christina TischerGlobal Foundation for the Care of Newborn Infants (GFCNI), Hofmannstraße 7a, 81378, Munich, Germany.ORCID http://orcid.org/0000-0001-6699-9484
Luc J I ZimmermannGlobal Foundation for the Care of Newborn Infants (GFCNI), Hofmannstraße 7a, 81378, Munich, Germany.ORCID http://orcid.org/0000-0002-1409-3821
ResQ Family study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRSV infections in children affect the entire family. Nevertheless, evidence on the overall impact is scarce. This multi-country observational study aims to investigate the association between disease severity and health-related quality of life (HRQoL) in affected families and to explore the role of factors related to mental well-being. METHODOLOGY: Data were collected during the 2022-2023 RSV season in Germany, France, Italy and Sweden via an online questionnaire from parents of children (24 months) hospitalised for RSV. Parental HRQoL was assessed using the validated caregiver-reported PedsQL Family Impact Module. Exploratory analyses and multivariate linear regression models were performed focusing on potential key determinants.

resultsA total set of 138 participants was assembled. Parents of children with a severe RSV infection had on average - 12.1 [95% CI: -21.2 to - 3.03; P = 0.010] lower HRQoL Summary Score than parents of children with low severity index scores. Subsequent stratified analyses revealed a stronger association among parents who had not been offered (adequate) mental health support.

conclusionHigher RSV disease severity was associated with lower parental HRQoL. These findings highlight the importance of preventing severe RSV infection and the need for further research to identify and evaluate appropriate (psychosocial) support for affected families.

trial registrationClinicalTrials.gov, identifier, NCT05550545. Registered 12 September 2022.

Indexed as

ParentsQuality of LifeRespiratory Syncytial Virus InfectionsAdultChild, PreschoolEuropeFemaleHumansInfantMaleSeverity of Illness IndexSurveys and QuestionnairesFamilyHRQoLQuality of lifeRespiratory syncytial virusRSV

Identifiers

PMID42507294
PMCPMC13407400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.