Evidence map›Paper›PMID 42507209›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Audiometric indicators of cochlear involvement in chronic suppurative otitis media with and without cholesteatoma.

Ahmed Mohammed Abdelghany, Osama Ahmed Ali Elsayad, Fatma Gamal Abdelmonged Saleh, Noha Mohamed Magdi Zaki

Abstract readComparative Study
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ahmed Mohammed AbdelghanyOtorhinolaryngology Department, Benha University, Farid Nada Street, Benha, Qalyubia, 13518, Egypt. ahmedent@gmail.com.ORCID http://orcid.org/0000-0003-4781-4661
Osama Ahmed Ali ElsayadOtorhinolaryngology Department, Benha University, Farid Nada Street, Benha, Qalyubia, 13518, Egypt.
Fatma Gamal Abdelmonged SalehFaculty of Medicine Benha University, Benha, Egypt.
Noha Mohamed Magdi ZakiOtorhinolaryngology Department, Benha University, Farid Nada Street, Benha, Qalyubia, 13518, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to compare cochlear function in patients with chronic suppurative otitis media (CSOM) with and without cholesteatoma and to identify clinical predictors of mixed hearing loss.

methodsA retrospective comparative study conducted at the Otorhinolaryngology Department, Benha University Hospitals, Egypt, from April 2024 to April 2025. Sixty-two patients with unilateral CSOM and complete audiologic and radiologic data were included, comprising 30 with cholesteatoma and 32 without. Evaluations included pure-tone audiometry, speech reception threshold (SRT), speech discrimination score (SDS), and temporal bone computed tomography. Cholesteatoma severity was staged using the EAONO/JOS classification. Multivariate regression analyses were performed to identify factors associated with mixed hearing loss and air- and bone-conduction pure-tone averages (PTA), with bone-conduction PTA serving as a surrogate for cochlear involvement.

resultsDisease duration was significantly longer in the cholesteatoma group (P = 0.023), while other baseline characteristics were comparable. Hearing metrics (PTA, SRT, SDS) did not differ significantly between groups. Multivariate analysis identified advancing age and longer disease duration as independent predictors of mixed hearing loss, whereas the presence of cholesteatoma was not.

conclusionCholesteatoma was associated with longer disease duration but was not independently associated with measurable cochlear involvement, based on the audiometric measures and cross-sectional design employed. Age and disease chronicity were the primary determinants of audiometric patterns compatible with cochlear involvement, underscoring the importance of early diagnosis and timely management.

Indexed as

Cholesteatoma, Middle EarCochleaHearing Loss, Mixed Conductive-SensorineuralOtitis Media, SuppurativeAdolescentAdultAudiometry, Pure-ToneAuditory AcuityBone ConductionChronic DiseaseFemaleHumansMaleMiddle AgedRetrospective StudiesSpeech Reception Threshold TestCholesteatomaChronic Suppurative Otitis MediaMixed Hearing Loss

Identifiers

PMID42507209
PMCPMC13615016

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.