Evidence map›Paper›PMID 42507175›Full record

ArticleMikrochimica acta2026

Photothermal and colorimetric dual mode assay based on nanozymes for gastric cancer exosomes.

Jinhu Chen, He Huang, Yi Zeng, Xiaopeng Wang, Shu Chen, Jianping Jiang, Youping Xiao, Miao Zheng, Xiandong Lin, Zaisheng Ye

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jinhu Chen *Department of Gastric Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China.
He Huang *Endoscopy Center, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China.
Yi Zeng *Department of Gastric Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China.
Xiaopeng WangDepartment of Gastric Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China.
Shu ChenDepartment of Gastric Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China.
Jianping JiangDepartment of Gastric Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China.
Youping XiaoDepartment of Radiology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China. xyp999@yeah.net.
Miao ZhengDepartment of Clinical Laboratory, Fujian Provincial Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, 350001, China. 86259132@qq.com.
Xiandong LinLaboratory of Radiation Oncology and Radiobiology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China. linxdong1970@fjzlhospital.com.
Zaisheng YeDepartment of Gastric Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No. 420 Fuma Road, Fuzhou, Fujian Province, 350014, China. flyingengel88@sina.com.

Funding

Fujian Provincial Health and Medical Innovation Project 2023CXA038Fujian Provincial Young and Middle-aged Health Leading Talent Training Program 2023-2839High-level Talent Program of Fujian Cancer Hospital 2022YNG10Joint Funds for the Innovation of Science and Technology, Fujian Province 2024Y9623National Natural Science Foundation of China 82403013Science and Technology Program of Fujian Province 2025J011174Science and Technology Program of Fujian Province 2025J011175the Institutional Funding Project of Fujian Cancer Hospital F2426C-BZ01-01The Joint Funds for the Innovation of Science and Technology of Fujian Province 2025Y9668
6 · The paper itself

Abstract

Exosome analysis in gastric cancer (GC) serum requires sensitive readout with reduced matrix interference. Circulating GC-related CD63-positive exosomes can indicate vesicle burden and stress-induced secretion. Herein, we developed a dual-mode photothermal/colorimetric aptasensor using CD63 aptamer-functionalized core-shell AuPt nanozymes for detecting GC-related CD63-positive exosomes in serum samples. The innovation of this platform lies in integrating aptamer recognition, Pt-shell peroxidase-like catalysis, and Au-core near-infrared (NIR) photothermal conversion within one nanoprobe. The porous Pt shell showed high TMB affinity (K

Indexed as

Biosensing TechniquesColorimetryExosomesMetal NanoparticlesStomach NeoplasmsAptamers, NucleotideGoldHumansLimit of DetectionPlatinumTetraspanin 30Aptamers, NucleotideCD63 protein, humanGoldPlatinumTetraspanin 30AuPt nanozymesDual-mode aptasensorGastric cancer exosomesLiquid biopsyPhotothermal assaySmartphone RGB analysis

Identifiers

PMID42507175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.