Evidence map›Paper›PMID 42506997›Full record

ArticleMikrochimica acta2026

DNA tetrahedrons based DNA microcapsules for sensitive fluorescence sensing of Staphylococcus aureus.

Zongbing Li, Yanyang Cui, Zhouqi Pan, Qiumei Feng, Xiangmin Miao, Yongguang Gao

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zongbing LiSchool of Life Science, Jiangsu Normal University, Xuzhou, 221116, China.
Yanyang CuiSchool of Life Science, Jiangsu Normal University, Xuzhou, 221116, China.
Zhouqi PanSchool of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, 221116, China.
Qiumei FengSchool of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, 221116, China. fengqiumei@jsnu.edu.cn.
Xiangmin MiaoSchool of Life Science, Jiangsu Normal University, Xuzhou, 221116, China. mxm0107@jsnu.edu.cn.
Yongguang GaoXuzhou Central Hospital, Southeast University Affiliated Xuzhou Central Hospital, 199 Jiefang Road, Xuzhou, 221009, China. saga0320@sina.com.

Funding

the Scientific Research Support Project for Teachers with Doctor's Degrees 24XFRS044
6 · The paper itself

Abstract

A sensitive fluorescence (FL) biosensor was developed for the detection of Staphylococcus aureus (S. aureus) using DNA tetrahedrons (DTNs) based stimuli-responsive DNA microcapsules. FAM-labeled DTNs were initially encapsulated within the inner pores of DNA microcapsules. Owing to the physical shielding effect of the DNA shell, no FL signal was detected, maintaining the biosensor in a "fluorescence off" state. Upon exposure to S. aureus, the aptamer specifically bound to the target bacteria, triggering the disassembly of the DTN-loaded DNA microcapsules. This led to the controlled release of FAM-labeled DTNs and the subsequent recovery of the FL signal. Based on this, sensitive and specific detection of S. aureus was achieved with a detection limit of 0.36 CFU∙mL

Indexed as

Biosensing TechniquesDNAStaphylococcus aureusAnimalsAptamers, NucleotideCapsulesDNA NanostructuresFluorescenceFluorescent Chemosensor CompoundsFluorescent DyesHumansLimit of DetectionMilkSpectrometry, FluorescenceSpinacia oleraceaAptamers, NucleotideCapsulesDNAFluorescent Chemosensor CompoundsFluorescent DyesBiosensorDNA microcapsulesDNA tetrahedronsFluorescence detectionS. aureus

Identifiers

PMID42506997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.