Evidence map›Paper›PMID 42506994›Full record

ArticleArchives of gynecology and obstetrics2026

Real-word evidence on the effectiveness of the Endo-App in reducing endometriosis-related complaints: a retrospective analysis.

Meletios P Nigdelis, Christine Anderl, Erich-Franz Solomayer, Martin Sillem

Abstract read
In one paragraph

Article in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Is the reported benefit of the Endo-App truly sustained?Archives of gynecology and obstetrics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meletios P NigdelisDepartment of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Germany. meletios.nigdelis@uks.eu.ORCID http://orcid.org/0000-0003-3865-6833
Christine AnderlEndo Health GmbH, Chemnitz, Germany.
Erich-Franz SolomayerDepartment of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Germany.
Martin SillemDepartment of Gynecology, Obstetrics, and Reproductive Medicine, Saarland University Medical Center, Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRandomized controlled clinical trials have shown that symptoms of chronic pain conditions, such as endometriosis, can be improved with the use of specialized health apps. In the current study, real-world evidence was collected from Endo-App users to determine whether there was a sustained and positive effect on endometriosis symptoms.

methodsUsers of the Endo-App were offered an optional, six-question anonymous survey through the platform upon first registration (T0), after 3 (T1), and 6 to 7 (T3) months of use. The survey questions were not standardized and aimed to assess the severity of endometriosis symptoms and overall quality of life. Data were analyzed using MatLab using a parametric paired t-test when pairs of data between T0-T1 and/or T0-T2 were available. Statistical significance was defined as p < 0.05.

resultsA total of 143 users of the app completed at least part of the survey at 3 months and 55 users at 6 to 7 months. After 3 and 6 to 7 months of using the app average pain levels and days requiring medical assistance were significantly reduced compared to baseline values. In addition, the average reported number of sick days taken was significantly reduced at the 6-to-7-month timepoint compared to baseline.

conclusionThis real-world study demonstrates that use of a specialized app for endometriosis, such as the Endo-App, documents and may lead to a significant and sustained improvement of some endometriosis symptoms.

Indexed as

EndometriosisMobile ApplicationsPelvic PainAdultChronic PainFemaleHumansMiddle AgedQuality of LifeRetrospective StudiesSurveys and QuestionnairesAppDigital healthEndometriosisPelvic painReal-world evidence

Identifiers

PMID42506994
PMCPMC13407453

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.