Evidence map›Paper›PMID 42506940›Full record

ArticleJournal of clinical microbiology2026

Applicability of Nanopore-only whole-genome sequencing for

J Dingemans, S Vandersanden, P Hilkens, J Godelaine, K Magerman, F Crombé, D De Geyter, A Boel, P Bruynseels, J Frans and 3 more

Abstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

J Dingemans *Clinical Laboratory of Molecular Microbiology, Jessa Hospital, Hasselt, Belgium.ORCID 0000-0001-8079-3087
S Vandersanden *Clinical Laboratory of Molecular Microbiology, Jessa Hospital, Hasselt, Belgium.
P HilkensClinical Laboratory of Microbiology, Jessa Hospital, Hasselt, Belgium.
J GodelaineClinical Laboratory of Microbiology, Jessa Hospital, Hasselt, Belgium.
K MagermanClinical Laboratory of Molecular Microbiology, Jessa Hospital, Hasselt, Belgium.
F CrombéDepartment of Microbiology and Infection Control, Vitality Research Group, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.
D De GeyterDepartment of Microbiology and Infection Control, Vitality Research Group, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.
A BoelDepartment of Laboratory Medicine, AZORG, Aalst, Belgium.
P BruynseelsDepartment of Laboratory Medicine, Ziekenhuis aan de Stroom, Antwerp, Belgium.
J FransDepartment of Clinical Microbiology, Imelda Hospital, Bonheiden, Belgium.
P VandecandelaereDepartment of Laboratory Medicine, Jan Yperman Hospital, Ypres, Belgium.
A M Van den AbeeleDepartment of Laboratory Medicine, AZ Sint-Lucas Ghent, Ghent, Belgium.
R CartuyvelsClinical Laboratory of Molecular Microbiology, Jessa Hospital, Hasselt, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IMPORTANCE: In recent years, Nanopore sequencing has found its way to clinical laboratories because of its affordability, scalability, and, most importantly, its ability to obtain sequencing results in near-real time. However, despite improved raw read accuracies with the latest generation R10.4.1 flow cells, the question remains whether the achieved accuracy is sufficient for accurate bacterial outbreak investigation, particularly in high-risk settings such as intensive care units (ICUs). In this study, we show that Nanopore-only whole-genome sequencing (WGS) is able to match Illumina-only WGS in terms of accuracy for

Indexed as

Disease OutbreaksIntensive Care UnitsPseudomonas aeruginosaPseudomonas InfectionsWhole Genome SequencingBelgiumDrug Resistance, BacterialGenome, BacterialGenotypeHumansMolecular EpidemiologyNanoporesNanopore Sequencingintensive care unitNanopore-only WGSoutbreak investigationPseudomonas aeruginosa

Identifiers

PMID42506940
PMCPMC13464046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.