ArticleVaccines2026
A Multi-State, Cross-Sectional Retrospective Study on Knowledge, Attitude and Practice of Rabies Post-Exposure Prophylaxis Including Rabies Monoclonal Antibody Among Physicians Across India.
Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
BACKGROUND/
objectivesRabies remains a lethal vaccine-preventable disease in India, and physicians managing animal-bite cases are central to effective post-exposure prophylaxis (PEP). With the increasing use of rabies monoclonal antibodies (RmAbs) as alternatives to conventional rabies immunoglobulins, this study assessed physicians' knowledge, attitude, and practice (KAP) regarding rabies PEP, including RmAb awareness and acceptance.
methodsThis multi-state, cross-sectional retrospective KAP survey was conducted among 208 physicians across ten Indian states using a structured, self-administered Google Form. The 33-item questionnaire assessed Knowledge, Attitude, and Practice domains, with 11 items each, scored binarily according to NCDC guidelines. Descriptive statistics, Shapiro-Wilk normality testing, Kruskal-Wallis tests with post hoc corrections, and Spearman rank-order correlations were performed.
resultsMean domain scores were 8.00/11 for Knowledge (72.7%), 7.22/11 for Attitude (65.6%), and 8.64/11 for Practice (78.5%). Key gaps were identified in the intramuscular pre-exposure prophylaxis schedule, management of excess RIG/RmAb after wound infiltration, exposure categorization of animal contact, and vaccine administration site in young children. The Knowledge-Practice correlation was moderately strong and statistically significant (r = 0.520,
conclusionsOverall KAP scores were adequate, with Practice scoring highest. Targeted continuing medical education focused on NCDC guidelines and practical PEP scenarios is needed among physicians managing rabies exposures.
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