Evidence map›Paper›PMID 42506632›Full record

ArticleVaccines2026

Post-Pandemic Resurgence of Pertussis in Southeastern Romania, 2024: Vaccination Gaps, Clinical Severity, and Regional Surveillance Performance.

Alina Plesea Condratovici, Mihaela Debita, Valerian Ionut Stoian, Catalin Plesea Condratovici, Ancuta Elena Tupu, Simona Steliana Tudor

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alina Plesea CondratoviciFaculty of Medicine and Pharmacy, Medical-Pharmaceutical Research Center, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0000-0002-2710-7284
Mihaela DebitaFaculty of Medicine and Pharmacy, Medical-Pharmaceutical Research Center, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.
Valerian Ionut StoianFaculty of Medicine and Pharmacy, Medical-Pharmaceutical Research Center, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0000-0003-4739-9197
Catalin Plesea CondratoviciFaculty of Medicine and Pharmacy, Medical-Pharmaceutical Research Center, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0000-0003-3111-4089
Ancuta Elena TupuFaculty of Medicine and Pharmacy, Medical-Pharmaceutical Research Center, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0009-0006-3855-2056
Simona Steliana TudorFaculty of Medicine and Pharmacy, Medical-Pharmaceutical Research Center, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.

Funding

"Dunarea de Jos" University of Galati VAT number RO50411550
6 · The paper itself

Abstract

BACKGROUND/

objectivesFollowing the COVID-19 pandemic, pertussis resurged sharply across Europe, with 209,674 cases reported in the EU/EEA in 2024. This study characterises the epidemiology of the 2024 pertussis resurgence across five counties of southeastern Romania, with emphasis on vaccination status, clinical severity, and regional surveillance performance.

methodsA retrospective, population-based analysis was conducted on 452 cases notified between February 2024 and January 2025, extracted from the national surveillance database. A pre-specified reclassification of PCR-positive cases yielded 326 confirmed cases. Categorical, non-parametric, correlation, and multivariate logistic regression analyses were performed.

resultsThe epidemic peaked in September 2024, with 56.0% of cases occurring between August and October. Children under five years accounted for 63.2% of confirmed cases, and 72.1% were not vaccinated according to age-appropriate schedule, predominantly due to parental refusal (43.0%) and non-attendance (36.6%). Pneumonia affected 36.8% of confirmed cases, ranging from 81.0% in infants under two months to 0% in adolescents. Age-appropriate vaccination was independently protective against pneumonia (adjusted OR = 0.53, 95% CI 0.29 to 0.96,

conclusionsVaccination gaps were the principal modifiable driver of the resurgence, supporting targeted coverage improvement and the introduction of a national maternal Tdap programme.

Indexed as

Bordetella pertussisepidemiological surveillanceimmunity debtlogistic regressionpertussispneumoniapost-pandemic resurgenceRomaniavaccination coveragewhooping cough

Identifiers

PMID42506632
PMCPMC13418353

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.