Evidence map›Paper›PMID 42506595›Full record

ArticleVaccines2026

Immunogenicity of an Oil-in-Water Emulsion Containing

Ri Ra Hong, Eun Ji Lee, Ji Hee Kwon, Sun Woo Im, Yeji Nam, Hyun-Tae Son, Eunhye Yoo, Hyung Tae Lee

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ri Ra HongEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.
Eun Ji LeeEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.
Ji Hee KwonEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.
Sun Woo ImEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.
Yeji NamEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.
Hyun-Tae SonEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.
Eunhye YooEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.
Hyung Tae LeeEutilex Co., Ltd., Gasan Digital 1-Ro 58, Geumcheon-gu, Seoul 08591, Republic of Korea.ORCID 0000-0002-1081-7933

Funding

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries RS-2025-02304147
6 · The paper itself

Abstract

backgroundLipopolysaccharide (LPS) functions as a Toll-like receptor 4 (TLR4) agonist that triggers innate immunity; however, structural variations between pathogenic and commensal bacteria distinctly influence its immunostimulatory profile. This study evaluated the immunostimulatory activity of LPS derived from the commensal bacterium

methodsCytokine induction was evaluated in immune cells across diverse host species, and receptor activation was assessed via reporter assays. To investigate in vivo immunogenicity and preliminary tolerability,

resultsLPS from

conclusions

Indexed as

Dectin-2Hafnia alveilipopolysaccharide (LPS)oil-in-water (O/W) emulsionTLR4vaccine adjuvant

Identifiers

PMID42506595
PMCPMC13417346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.