Evidence map›Paper›PMID 42506542›Full record

ArticleJournal of functional biomaterials2026

Synergizing Macrogeometric Design and Nano-Hydroxyapatite Coatings to Enhance Early Implant Stability and Bone Maturation.

Ana Carolina Loyola Barbosa, Rafaella da Cruz Polizelli Scannavino, Uislen Berian Cadore, Arthur Belem Novaes Junior, Bruna Ghiraldini, Roberto Sales E Pessoa, Sergio Scombatti de Souza

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Carolina Loyola BarbosaSchool of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0001-8711-6791
Rafaella da Cruz Polizelli ScannavinoSchool of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.
Uislen Berian CadoreSchool of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.
Arthur Belem Novaes JuniorSchool of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-1982-6756
Bruna GhiraldiniResearch & Development Department, S.I.N. Implant System, São Paulo 03033-021, SP, Brazil.ORCID 0000-0002-3693-3035
Roberto Sales E PessoaResearch & Development Department, S.I.N. Implant System, São Paulo 03033-021, SP, Brazil.ORCID 0000-0003-1763-3691
Sergio Scombatti de SouzaSchool of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-904, SP, Brazil.ORCID 0000-0002-6199-7348

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo - FAPESP 2023/11553-2
6 · The paper itself

Abstract

Implant macrogeometry and surface microstructure represent fundamental pillars for accelerating and enhancing the quality of osseointegration. The objective of this study was to evaluate the synergistic effect of three distinct implant designs, Strong (hybrid with trapezoidal threads), Unitite (hybrid with healing chambers), and Epikut (hybrid with active double threads), associated with two surface configurations (dual acid-etched [DAE] and nanohydroxyapatite [NanoHA]) on bone regeneration at 3 and 8 weeks. Twenty-four male rabbits randomly received forty-eight implants in their tibiae, yielding an equal accounting of

Indexed as

biomechanicsdental implantsmacrogeometrymicro-computed tomographyosseointegrationsurface treatment

Identifiers

PMID42506542
PMCPMC13412758

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.