Evidence map›Paper›PMID 42506540›Full record

ArticleJournal of functional biomaterials2026

A Multimodal Assessment of a New Self-Adhering Flowable Composite: Dental Pulp Stem Cell Viability and Bond Strength.

Jiayuan Zhang, Chiharu Kawamoto, Ryotaro Yago, Hidehiko Sano, Fumiko Minowa, Asiful Islam, Rin Miyake, Yunqing Liu, Atsushi Tomokiyo

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiayuan ZhangDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.ORCID 0009-0002-2874-8697
Chiharu KawamotoDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.ORCID 0009-0003-4900-3368
Ryotaro YagoDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.ORCID 0009-0002-5142-739X
Hidehiko SanoDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.ORCID 0000-0003-1505-4047
Fumiko MinowaDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.
Asiful IslamDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.ORCID 0009-0004-5113-4882
Rin MiyakeDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.
Yunqing LiuDepartment of Stomatology, The Forth Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Atsushi TomokiyoDepartment of Restorative Dentistry, Faculty of Dental Medicine, Hokkaido University, Sapporo 0608586, Japan.

Funding

Japan Science and Technology Agency JPMJSP2119Japan Society for the Promotion of Science JP22K09994Japan Society for the Promotion of Science JP25K13014Japan Society for the Promotion of Science JP25K22677
6 · The paper itself

Abstract

Self-adhering flowable composites (SAFCs) were developed to simplify restorative procedures by eliminating separate adhesive steps; however, their bonding performance, mechanical properties, and biological properties remain controversial. This study evaluated a newly developed SAFC (SA-100R) compared with three commercial SAFCs (Fusio Liquid Dentin, Constic, and Vertise Flow) and a conventional composite (Clearfil AP-X used with a two-step self-etch adhesive). Microtensile bond strength (μTBS) to dentin, failure modes, Knoop microhardness, resin-dentin interfacial morphology (SEM), elemental composition (EDX), and cytocompatibility (CCK-8, LIVE/DEAD staining) were assessed. The conventional composite system exhibited significantly higher µTBS than all SAFCs (

Indexed as

biocompatibilitydental pulp stem cellsdentin bond strengthmicrohardnessself-adhering flowable composite

Identifiers

PMID42506540
PMCPMC13413257

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.