Evidence map›Paper›PMID 42506423›Full record

ArticleMetabolites2026

Effects of Fluoride and 8:2 FTOH on β-Cell Calcium Signaling and Insulin Homeostasis: An Exploratory Study.

Juliana Sanches Trevizol, Motoki Okamoto, Shohei Yamashita, Nanako Kuriki, Susanne Brueckner, Satoru Shindo, Toshihisa Kawai, Raissa Estefane Vaz Damião, Aline Dionizio, Marilia Afonso Rabelo Buzalaf and 1 more

Abstract read
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juliana Sanches TrevizolDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.ORCID 0000-0001-7452-661X
Motoki OkamotoDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.ORCID 0000-0002-3759-5031
Shohei YamashitaDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.ORCID 0009-0009-4360-2830
Nanako KurikiDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Susanne BruecknerDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Satoru ShindoDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Toshihisa KawaiDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Raissa Estefane Vaz DamiãoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-902, São Paulo, Brazil.ORCID 0009-0007-8728-4788
Aline DionizioDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-902, São Paulo, Brazil.ORCID 0000-0002-8687-0124
Marilia Afonso Rabelo BuzalafDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-902, São Paulo, Brazil.ORCID 0000-0002-5985-3951
Maiko SuzukiDepartment of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.ORCID 0000-0002-1732-0663

Funding

Epigenetic and Non-epigenetic Role of SIRT1 in Fluoride-induced Cell Stress Administrative Supplement.R01DE027648 · NIDCR · OHIO STATE UNIVERSITY · PI SUZUKI, MAIKO · 2018 to 2024
$2.2M
Health Effects of the Fluorinated Pollutants; PFAS on Enamel DevelopmentK02DE029531 · NIDCR · NOVA SOUTHEASTERN UNIVERSITY · PI SUZUKI, MAIKO · 2022 to 2024
$428k
Fundação de Amparo à Pesquisa do Estado de São Paulo 2024/07452-9 and 2019/26070-1NIDCR NIH HHS K02 DE029531NIDCR NIH HHS R01 DE027648
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

calciumfluorideFTOHpancreasPFASβ-cells

Identifiers

PMID42506423
PMCPMC13413545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.