Evidence map›Paper›PMID 42506415›Full record

ArticleMetabolites2026

GABA Regulates Ca

Vladimir Grubelnik, Marko Marhl

Abstract read
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vladimir GrubelnikFaculty of Electrical Engineering and Computer Science, University of Maribor, Koroška cesta 46, 2000 Maribor, Slovenia.ORCID 0000-0002-4182-8520
Marko MarhlFaculty of Natural Sciences and Mathematics, University of Maribor, Koroška cesta 160, 2000 Maribor, Slovenia.ORCID 0000-0003-0387-1162

Funding

The Slovenian Research and Innovation Agency J3-60062The Slovenian Research and Innovation Agency P1-0055
6 · The paper itself

Abstract

BACKGROUND/

objectivesGamma-aminobutyric acid (GABA) is increasingly recognized as an important modulator of pancreatic beta-cell function, but the mechanisms by which it regulates intracellular Ca

methodsWe developed a reduced ATP-Ca

resultsThe model reproduced key experimental observations under both control and GABA-deficient conditions, including reduced Ca

conclusionsGABA acts as a dual regulator of beta-cell dynamics, linking intracellular metabolism to Ca

Indexed as

ATP dynamicsCa2+ oscillationsentrainmentGABAGABA shuntmathematical modelingpancreatic beta cellssynchronization

Identifiers

PMID42506415
PMCPMC13413645

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.