Evidence map›Paper›PMID 42506398›Full record

ArticleMetabolites2026

Plasma Aromatic L-Amino Acid Decarboxylase Activity by HPLC as a Functional Biomarker for the Diagnosis of Aromatic L-Amino Acid Decarboxylase Deficiency.

Norashareena Mohamed Shakrin, Norzahidah Khalid, Nor Azimah Abdul Azize, Yusnita Yakob, Abdah Md Akim, Julaina Abdul Jalil

Abstract read
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Norashareena Mohamed ShakrinInborn Errors of Metabolism & Genetics Unit, Nutrition, Metabolic & Cardiovascular Research Centre, Institute for Medical Research (IMR), National Institutes of Health (NIH), Ministry of Health Malaysia, Persiaran Setia Murni U13/52, Bandar Setia Alam, Shah Alam 40170, Malaysia.ORCID 0009-0003-3498-3690
Norzahidah KhalidBiochemistry Unit, Specialized Diagnostic Centre, Institute for Medical Research (IMR), National Institutes of Health (NIH), Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur 50588, Malaysia.ORCID 0009-0007-5361-2018
Nor Azimah Abdul AzizeMolecular Diagnostics Unit, Specialized Diagnostic Centre, Institute for Medical Research (IMR), National Institutes of Health (NIH), Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur 50588, Malaysia.
Yusnita YakobMolecular Diagnostics Unit, Specialized Diagnostic Centre, Institute for Medical Research (IMR), National Institutes of Health (NIH), Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur 50588, Malaysia.
Abdah Md AkimDepartment of Biomedical Sciences, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia (UPM), Serdang 43400, Malaysia.ORCID 0000-0001-5989-5804
Julaina Abdul JalilInborn Errors of Metabolism & Genetics Unit, Nutrition, Metabolic & Cardiovascular Research Centre, Institute for Medical Research (IMR), National Institutes of Health (NIH), Ministry of Health Malaysia, Persiaran Setia Murni U13/52, Bandar Setia Alam, Shah Alam 40170, Malaysia.ORCID 0009-0009-7542-2922

Funding

National Institute of Health, Malaysia NMRR-19-196-46731
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aromatic-L-amino acid decarboxylase deficiencybiomarkersclinical metabolomicsDDC genedopamineHigh-Performance Liquid ChromatographyInborn errors of metabolismserotonin

Identifiers

PMID42506398
PMCPMC13414192

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.