Evidence map›Paper›PMID 42506357›Full record

SynthesisMedical sciences (Basel, Switzerland)2026

Interventions to Promote Communication in Minimally Verbal Autistic Children: A Systematic Review.

Roberta Privitera, Adriana Piccolo, Carmela De Domenico, Giulia Leonardi, Angelo Alito, Angelo Quartarone, Francesca Cucinotta, Marcella Di Cara

Abstract readSystematic Review
In one paragraph

Synthesis in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Roberta PriviteraIRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy.
Adriana PiccoloIRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy.
Carmela De DomenicoIRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy.ORCID 0009-0007-8868-8485
Giulia LeonardiDepartment of Physical and Rehabilitation Medicine, University Hospital "G. Martino", 98124 Messina, Italy.ORCID 0000-0002-9532-0220
Angelo AlitoDepartment of Biomedical, Dental Sciences and Morphological and Functional Images, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-6609-579X
Angelo QuartaroneIRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy.
Francesca CucinottaIRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy.ORCID 0000-0001-8477-7826
Marcella Di CaraIRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C. da Casazza, 98124 Messina, Italy.ORCID 0000-0002-4275-4340

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesMinimally verbal autistic children face profound communication challenges that significantly affect daily functioning, including social interaction, behavioral regulation, and overall well-being. Identifying effective interventions is a key clinical-educational priority. This systematic review examines communication-focused interventions for these children, including both spoken language approaches and augmentative and alternative communication (AAC) strategies.

methodsThe review was registered in PROSPERO and conducted following PRISMA-S guidelines. Four electronic databases were searched, and 18 studies met the inclusion criteria. Due to heterogeneity in study designs and outcome measures, a narrative synthesis was conducted, with subgroup analyses exploring sample characteristics, intervention types, targeted outcomes, and reported effects. Methodological quality of randomized controlled trials was assessed using the Cochrane Risk of Bias tool.

resultsInterventions were implemented across clinical, educational, and home settings, using strategies such as Joint Attention, Symbolic Play, and Emotion Regulation, often combined with AAC technologies. Most included studies reported improvements in at least one communication outcome, although findings were heterogeneous and several studies reported mixed, subgroup-specific, or non-significant effects. The most consistent improvements were observed in spontaneous communication, particularly in interventions integrating developmental approaches with technological support.

conclusionsThese findings highlight the value of individualized interventions. Future research should establish standardized definitions of "minimally verbal", assess long-term outcomes, and adopt broader measures capturing both language and social-emotional development to enhance quality of life and inclusion.

Indexed as

Autistic DisorderCommunicationCommunication DisordersChildChild, PreschoolCommunication Devices for People with DisabilitiesHumansautism spectrum disordercommunicationinterventionsminimally verbalrehabilitationsystematic review

Identifiers

PMID42506357
PMCPMC13414371

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.