Evidence map›Paper›PMID 42506255›Full record

ArticleJournal of fungi (Basel, Switzerland)2026

Beyond Single Enzymes: System-Level Fungal Transformation of Halogenated Nitrophenols.

Gerardo Aguilar, Christian Krohn, Alexis Marshall, Sali Khair Biek, Julie A Besedin, Courtney Pilcher, Attila Tottszer, Leadin S Khudur, Andrew S Ball

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gerardo AguilarDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.
Christian KrohnDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.ORCID 0000-0001-8255-4215
Alexis MarshallDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.ORCID 0000-0003-1990-6411
Sali Khair BiekDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.
Julie A BesedinDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.ORCID 0009-0007-1156-365X
Courtney PilcherDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.
Attila TottszerALS Environmental Smithfield, NSW, Australia.
Leadin S KhudurDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.ORCID 0000-0002-4593-3010
Andrew S BallDepartment of Biology, School of Science, RMIT University, Melbourne, VIC 3083, Australia.ORCID 0000-0003-2387-968X

Funding

Grantham Foundation PRJ00003509
6 · The paper itself

Abstract

Despite increasing interest in fungal remediation systems for the treatment of persistent contaminants, the mechanisms governing fungal transformation of halogenated organic compounds remain poorly resolved. The aim of this study was to determine whether the transformation of halogenated nitrophenols is driven by isolated extracellular enzymes and cofactor-dependent oxidative activity or instead reflects coordinated system-level fungal metabolism. To address this question, we investigated the transformation of 2-chloro-4-nitrophenol (2C4NP) and 5-fluoro-2-nitrophenol (5F2NP) by ascomycete fungi

Indexed as

biological transformationbioremediationbiotransformationenvironmental pollutionfungimetabolic pathwayorganic contaminantssystem-level process

Identifiers

PMID42506255
PMCPMC13413372

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.