Iodinated Contrast Media Dose Protocols for Computed Tomography Investigations of the Abdomen: A Systematic Review and Meta-Analysis.

Evans Ohemeng, Andrew Donkor, Ijeoma Chinedum Anyitey-Kokor, Obed Kojo Otoo, Theophilus N Akudjedu, William Kwadwo Antwi, Yaw Amo Wiafe

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In one paragraph

Review in Journal of imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Evans OhemengDepartment of Medical Imaging, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, PMB UPO, Kumasi, Ghana.ORCID 0009-0002-4072-8728

Andrew DonkorDepartment of Medical Imaging, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, PMB UPO, Kumasi, Ghana.ORCID 0000-0002-6073-524X

Ijeoma Chinedum Anyitey-KokorDepartment of Medical Imaging, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, PMB UPO, Kumasi, Ghana.ORCID 0000-0002-9375-2281

Obed Kojo OtooDepartment of Medical Imaging, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, PMB UPO, Kumasi, Ghana.

Theophilus N AkudjeduInstitute of Medical Imaging & Visualisation, Department of Medical Science & Public Health, Faculty of Health & Social Sciences, Bournemouth University, 12 St Pauls Ln, Bournemouth BH8 8GP, UK.

William Kwadwo AntwiDepartment of Radiography, School of Biomedical and Allied Sciences, P.O. Box LG 143 Korle-Bu, Accra, Ghana.ORCID 0000-0002-6726-2342

Yaw Amo WiafeDepartment of Medical Imaging, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, PMB UPO, Kumasi, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While several dosing protocols for iodinated contrast media (ICM) exist, a consensus strategy for optimising the physical imaging signal in abdominal CT is lacking. This systematic review and meta-analysis evaluated the performance of individualised dosing protocols, specifically focusing on technical signal optimisation, clinical safety, potential material savings, and environmental sustainability. Electronic databases (Cochrane, Embase, Medline) were searched up to January 2026. Systematic synthesis of 23 studies (11,680 participants) compared protocols based on lean body weight (LBW), total body weight (TBW), fixed volume (FV) and software-assisted dosing. Meta-analyses assessed volume optimisation and hepatic enhancement, with evidence certainty evaluated via the GRADE framework. TBW-based dosing significantly reduced contrast volume by -8.74 mL compared to FV protocols (

Indexed as

abdominal imagingdosing protocolsiodinated contrast mediaorgan enhancementpotential material savingssustainability

Identifiers

PMID42506147

DOI10.3390/jimaging12070301

PMCPMC13412522

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.