Evidence map›Paper›PMID 42505881›Full record

ArticleJournal of cardiovascular development and disease2026

Effects of Exercise Training on Left Ventricular Hypertrophy and Cardiac Regulation in Elite Athletes: Insight from a Composite Index Proxy of Autonomic Control.

Gianluigi Oggionni, Giuseppina Bernardelli, Mara Malacarne, Massimo Pagani, Antonio Spataro, Antonio Pelliccia, Daniela Lucini

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gianluigi OggionniDepartment of Medical Biotechnology and Translational Medicine (Department of Excellence 2023-2027), University of Milan, 20129 Milan, Italy.ORCID 0009-0007-5108-2594
Giuseppina BernardelliDepartment of Clinical Sciences and Community Health (Department of Excellence 2023-2027), University of Milan, 20122 Milan, Italy.ORCID 0000-0001-6626-8526
Mara MalacarneDepartment of Medical Biotechnology and Translational Medicine (Department of Excellence 2023-2027), University of Milan, 20129 Milan, Italy.ORCID 0000-0003-3957-3781
Massimo PaganiExercise Medicine Unit, Istituto Auxologico Italiano, IRCCS, 20135 Milan, Italy.
Antonio SpataroDepartment of Medicine, Institute of Sport Medicine and Science, 00197 Rome, Italy.
Antonio PellicciaDepartment of Medicine, Institute of Sport Medicine and Science, 00197 Rome, Italy.
Daniela LuciniDepartment of Medical Biotechnology and Translational Medicine (Department of Excellence 2023-2027), University of Milan, 20129 Milan, Italy.ORCID 0000-0003-4845-8988

Funding

This research was partially funded by the Italian Ministry of Health
6 · The paper itself

Abstract

The "athlete's heart" represents a physiological condition consequent to long-term adaptation to sport-specific training loads. Cardiac imaging is a pivotal tool in the assessment of athletes. The study of the autonomic nervous system (ANS) using heart rate variability is becoming increasingly popular in sports fields, given its fundamental role in cardiovascular adaptation to exercise. Unfortunately, many barriers limit the clinical use of this methodology. In this observational study of 330 elite athletes, we used a composite index of ANS control (ANSI), designed to overcome pitfalls, following the hypothesis that studying the ANS could help address cardiac adaptation to high-volume training. In athletes subdivided into three groups considering the level (LOW/HIGH) of combined static/dynamic exercise and the presence [+]/absence [-] of left ventricular hypertrophy (LVH), we found that ANSI showed a progressive increase (LOW: 38.2 ± 27.6%; HIGH-LVH [-]: 52.1 ± 27.2%; HIGH-LVH [+]: 64.4 ± 24.9%, J-T test

Indexed as

athlete’s heartautonomic nervous systemcardiac imagingechocardiographyheart rate variabilityleft ventricular hypertrophysport cardiologyvagal activity

Identifiers

PMID42505881
PMCPMC13411814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.