Evidence map›Paper›PMID 42505599›Full record

ArticleAntibiotics (Basel, Switzerland)2026

Changes in Antimicrobial Resistance Patterns in Intensive Care Units Following the COVID-19 Pandemic: A 10-Year Retrospective Study from Türkiye.

Ayşe Çapar, Derya Özyiğitoğlu, Şeyma Başlılar, Mürşide Efil Erdoğan, Beril Balak, Betül Nur Doğan, Öznur Hun Aktaş, Ebru Korkmaz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Antimicrobial Resistance Profile ofAntibiotics (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ayşe ÇaparAnaesthesiology and Intensive Care Medicine, Sultan Abdulhamid Han Training and Research Hospital, 34668 Istanbul, Türkiye.ORCID 0000-0002-6485-342X
Derya ÖzyiğitoğluInfectious Diseases and Clinical Microbiology, Sultan Abdulhamid Han Training and Research Hospital, 34668 Istanbul, Türkiye.
Şeyma BaşlılarChest Diseases, Sultan Abdulhamid Han Training and Research Hospital, 34668 Istanbul, Türkiye.ORCID 0000-0003-1495-6508
Mürşide Efil ErdoğanPulmonary Intensive Care Unit, Sultan Abdulhamid Han Training and Research Hospital, 34668 Istanbul, Türkiye.ORCID 0009-0000-3959-3155
Beril BalakGeneral Practice, Chelsea and Westminster Hospital, London SW10 9NH, UK.ORCID 0000-0003-1983-9757
Betül Nur DoğanCardiothoracic Surgery Intensive Care Unit, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London W12 0HS, UK.
Öznur Hun AktaşChest Diseases, Sultan Abdulhamid Han Training and Research Hospital, 34668 Istanbul, Türkiye.
Ebru KorkmazChest Diseases, Sultan Abdulhamid Han Training and Research Hospital, 34668 Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) pandemic coincided with substantial changes in healthcare delivery and antimicrobial resistance (AMR) patterns worldwide, particularly in intensive care units (ICUs), where invasive procedures and broad-spectrum antibiotics are commonly used. Data from Türkiye remains limited.

methodsThis retrospective observational study evaluated bacterial and fungal isolates from adult ICU patients at a tertiary hospital from 2016 to 2025. Microorganisms were identified, and antimicrobial susceptibility testing was performed using standardized methods. Resistance patterns were compared between the pre-pandemic (January 2016-February 2020) and post-pandemic (March 2020-May 2025) periods.

resultsA total of 2666 patients and 5433 isolates were analyzed. Gram-negative pathogens showed marked increases in resistance: carbapenem and colistin resistance in

conclusionsSignificant differences in AMR patterns were observed between the pre- and post-pandemic periods in this ICU population. Higher resistance rates were observed among several clinically important bacterial pathogens, and

Indexed as

antimicrobial resistanceCandida aurisCOVID-19 pandemicGram-negative bacteriaintensive care unit

Identifiers

PMID42505599
PMCPMC13403379

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.