Evidence map›Paper›PMID 42505597›Full record

ReviewAntibiotics (Basel, Switzerland)2026

Resistance and Recalcitrance in Dermatophytosis: Mechanistic and Clinical Considerations for Keratinized Tissues.

Alfredo Valdez-Martinez, Roberto Arenas, Andrea Moreno-Salinas, Mariana Perez-Tristan, Maria Jose Gomez-Rico, Ivette Torres-Olguín, Claudia Erika Fuentes-Venado, Fernando Bastida-González, Erick Martínez-Herrera, Rodolfo Pinto-Almazán

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alfredo Valdez-MartinezSección de Micología, Hospital General "Dr. Manuel Gea González", Mexico City 14080, Mexico.ORCID 0009-0008-8660-7220
Roberto ArenasSección de Micología, Hospital General "Dr. Manuel Gea González", Mexico City 14080, Mexico.ORCID 0000-0002-2992-9564
Andrea Moreno-SalinasClínica Hospital Constitución, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Monterrey 64530, Mexico.ORCID 0000-0002-5321-8922
Mariana Perez-TristanClínica Hospital Constitución, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Monterrey 64530, Mexico.
Maria Jose Gomez-RicoClínica Hospital Constitución, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Monterrey 64530, Mexico.
Ivette Torres-OlguínClínica Hospital Constitución, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Monterrey 64530, Mexico.
Claudia Erika Fuentes-VenadoSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Mexico City 11340, Mexico.
Fernando Bastida-GonzálezLaboratorio de Biología Molecular, Laboratorio Estatal de Salud Pública del Estado de México, Toluca de Lerdo 50130, Mexico.
Erick Martínez-HerreraSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Mexico City 11340, Mexico.ORCID 0000-0001-7298-158X
Rodolfo Pinto-AlmazánSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Mexico City 11340, Mexico.ORCID 0000-0002-5210-5395

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatophytosis remains one of the most prevalent superficial fungal infections worldwide and is increasingly encountered as a persistent or difficult-to-treat syndrome. A major clinical problem is that apparent treatment failure is often attributed to antifungal resistance, although many cases are instead driven by diagnostic uncertainty, corticosteroid-modified disease, reinfection, inadequate exposure, poor adherence, and limited drug delivery within keratinized tissues. This narrative review was developed to clarify the distinction between true antifungal resistance and clinical recalcitrance, with particular attention to terbinafine-resistant

Indexed as

antifungal resistancedermatophytesdermatophytomadermatophytosisonychomycosisrecalcitrant dermatophytosisterbinafine resistancetherapeutic failuretinea incognitoTrichophyton indotineae

Identifiers

PMID42505597
PMCPMC13405947

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.