Evidence map›Paper›PMID 42505592›Full record

ArticleDiseases (Basel, Switzerland)2026

Culturable Nasal Bacteria in Chronic Rhinosinusitis with Nasal Polyps: A Single-Center Observational Pilot Study.

Camilla Laureti, Dario Benelli, Federica Zoccali, Gabriele Riccardi, Mattia Umberto Di Michele, Stefano Venarubea, Christian Barbato, Antonio Minni, Carla Petrella

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Camilla LauretiDivision of Otolaryngology-Head and Neck Surgery, Ospedale San Camillo de Lellis, Azienda Sanitaria Locale (ASL) Rieti, Sapienza University of Rome, 02100 Rieti, Italy.ORCID 0009-0007-8984-8188
Dario BenelliDepartment of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-1488-8392
Federica ZoccaliDivision of Otolaryngology-Head and Neck Surgery, Ospedale San Camillo de Lellis, Azienda Sanitaria Locale (ASL) Rieti, Sapienza University of Rome, 02100 Rieti, Italy.ORCID 0000-0001-5481-4307
Gabriele RiccardiDivision of Otolaryngology-Head and Neck Surgery, Ospedale San Camillo de Lellis, Azienda Sanitaria Locale (ASL) Rieti, Sapienza University of Rome, 02100 Rieti, Italy.ORCID 0000-0003-2696-1048
Mattia Umberto Di MicheleDepartment of Sense Organs (DOS), Sapienza University of Rome, 00161 Rome, Italy.
Stefano VenarubeaClinical Pathology, San Camillo de Lellis Hospital, 02100 Rieti, Italy.
Christian BarbatoInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), 00161 Rome, Italy.ORCID 0000-0003-1737-9064
Antonio MinniDivision of Otolaryngology-Head and Neck Surgery, Ospedale San Camillo de Lellis, Azienda Sanitaria Locale (ASL) Rieti, Sapienza University of Rome, 02100 Rieti, Italy.
Carla PetrellaInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), 00161 Rome, Italy.ORCID 0000-0003-0651-1816

Funding

Bank of Italy N.1500764/24
6 · The paper itself

Abstract

backgroundBacteria colonizing the nasal cavity contribute to mucosal homeostasis, and altered sinonasal bacterial communities have been associated with chronic rhinosinusitis with nasal polyps (CRSwNP). Whether routine, culture-based microbiology can distinguish the cultivable bacterial profile of CRSwNP patients from that of controls remains unclear.

methodsIn this single-center observational pilot study, middle-meatus swabs from 30 patients with CRSwNP and 30 controls were cultured on four media, and isolates were identified with the VITEK 2 system. For each species, presence or absence per subject was compared between groups using Fisher's exact test with Benjamini-Hochberg correction for multiple comparisons; the number of cultivable species per subject was compared with the Mann-Whitney test.

resultsThe two groups were comparable in age and sex. Patients yielded more cultivable bacterial species per subject than controls (mean 4.4 vs. 2.9; Mann-Whitney

conclusionsUsing routine culture, CRSwNP was characterized chiefly by a higher number of cultivable bacterial species, whereas individual species differences were not statistically robust. These hypothesis-generating findings warrant confirmation in larger, sequencing-based studies.

Indexed as

chronic rhinosinusitis with nasal polypsculturable bacterianasal swabpilot studyStaphylococcus

Identifiers

PMID42505592
PMCPMC13409259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.