ArticleDiseases (Basel, Switzerland)2026
The Effect of Pretreatment Cataract Surgery on Selective Laser Trabeculoplasty Outcomes: A One-Year Follow-Up Study.
Article in Diseases (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesWe aim to determine whether prior cataract surgery affects the intraocular pressure (IOP)-lowering effect of selective laser trabeculoplasty (SLT) in patients with primary open-angle glaucoma (POAG).
methodsThis prospective interventional cohort study initially included 92 patients with POAG who were inadequately controlled or intolerant to topical therapy and were treated with SLT. Of these, 84 patients completed all scheduled visits and constituted the final analyzed dataset. Patients were divided into phakic and pseudophakic groups, with cataract surgery performed at least one year before SLT in all pseudophakic eyes. All patients underwent standardized 360-degree SLT by a single specialist. The primary outcome was IOP reduction at one year. Secondary outcomes included percentage IOP reduction and treatment success, defined as ≥20% IOP reduction. Data were analyzed using Statistica
resultsBefore SLT, the median IOP was 20.5 mmHg in phakic eyes and 21 mmHg in pseudophakic eyes. One year after SLT, median IOP decreased insignificantly in phakic eyes (4.0 mmHg;
conclusionAlthough pseudophakic eyes showed greater unadjusted IOP reduction after SLT over one year, lens status was not an independent predictor after adjustment for potential confounders. Therefore, the observed pseudophakic advantage should be interpreted as a hypothesis-generating association warranting further research into the effect of pseudophakia on SLT response.
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