ReviewBiosensors2026
Evolution of Whole-Cell Biosensor Detection Technology for PAHs and Their Halogenated Derivatives Driven by Performance Requirements.
Review in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
Abstract
Polycyclic aromatic hydrocarbons (PAHs) and their halogenated derivatives are important targets in environmental monitoring and pollution control because of their persistence, bioaccumulation, and potential carcinogenicity. Reliable strategies for detecting these pollutants remain essential for environmental risk assessment. In recent years, microbial whole-cell biosensors have attracted increasing attention as analytical tools for pollutant detection and toxicity evaluation. These biosensors employ living cells to recognize target compounds and generate measurable signals through endogenous metabolic pathways and transcriptional regulatory networks. As a result, they can reflect biologically relevant responses and operate in complex environmental matrices, making them suitable for in situ monitoring. This review summarises recent advances in whole-cell biosensors for detecting PAHs and their halogenated derivatives. We discuss the design strategies for constructing these whole-cell biosensors and outline their technological development. Recent efforts to improve biosensor performance are also highlighted. Current research trends indicate a shift from optimizing individual genetic components to improving overall system robustness, standardized evaluation, and practical field deployment. These developments provide important insights for designing reliable and engineerable whole-cell biosensing platforms for monitoring PAHs and related pollutants.
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Registered trials
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