Evidence map›Paper›PMID 42505387›Full record

ArticleCells2026

Comparison of Cytokine Profiles in Ligamentum Flavum from Patients Undergoing Surgery for Lumbar Disc Herniation and Lumbar Spinal Stenosis: An Exploratory Study.

Li-Yu Fay, Chao-Hung Kuo, Yi-Hsuan Kuo, Ching-Jung Chen, Wang-Yu Hsu, Dann-Ying Liou, Ya-Tzu Chen, Kai-Ming Chang, Meng-Jen Lee, Jau-Ching Wu

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li-Yu FayDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0003-0914-8776
Chao-Hung KuoDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0001-5528-204X
Yi-Hsuan KuoDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
Ching-Jung ChenNeural Regeneration Laboratory, Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0002-0966-268X
Wang-Yu HsuNeural Regeneration Laboratory, Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
Dann-Ying LiouNeural Regeneration Laboratory, Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0001-7391-9868
Ya-Tzu ChenNeural Regeneration Laboratory, Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0009-0004-4612-4102
Kai-Ming ChangDepartment of Molecular Medicine, Koo Foundation Sun Yat-Sen Cancer Center, Taipei 11209, Taiwan.
Meng-Jen LeeDepartment of Applied Chemistry, Chaoyang University of Technology, Taichung 413310, Taiwan.ORCID 0000-0002-5332-8806
Jau-Ching WuDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0002-6996-3409

Funding

Ministry of Science and Technology MOST 110-2314-B-075 -044 -MY3National Science and Technology Council NSTC 113-2314-B-075-071-MY3 and NSTC 113-2314-B-A49-084-MY3Taipei Veterans General Hospital V103B-011,V112C-071,V112C-082,V113C-014,V114C-003,V115C-014
6 · The paper itself

Abstract

In spinal pathology, lumbar disc herniation (LDH) is typically contrasted with lumbar spinal stenosis (LSS) based on either its pathophysiology (structural compression vs. dynamic/vascular/degenerative changes) or its clinical presentation (acute radiculopathy vs. chronic claudication). We compared the ligamentum flavum (LF) tissue, primary LF cells, and serum cytokine profiles using human cytokine antibody arrays and Western blotting between patients with LDH (

Indexed as

CytokinesIntervertebral Disc DisplacementLigamentum FlavumLumbar VertebraeSpinal StenosisAdultAgedFemaleHumansMaleMiddle AgedCytokinescytokineshypertrophyintervertebral disc herniationligamentum flavumosteoprotegerinspinal stenosis

Identifiers

PMID42505387
PMCPMC13406297

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.