Evidence map›Paper›PMID 42505377›Full record

ArticleCells2026

Low-Glucose Metabolic Remodeling Drives Reversible Sequestration of Yeast S-Adenosylmethionine (AdoMet) Synthase.

Hasnat Ahmed, Ahmad Sleiman, Mohamad Rahal, Eyas Hanbali, Marwa Aboumourad, Daniel Adebayo, Eseiwi Obaseki, Lindsey Kreinbring, Scott Miller, Elias Ayoub and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hasnat AhmedBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Ahmad SleimanBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Mohamad RahalBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Eyas HanbaliBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Marwa AboumouradBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Daniel AdebayoBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Eseiwi ObasekiBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Lindsey KreinbringBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Scott MillerBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Elias AyoubBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Allison JacobsonBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Andrew RassamBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.
Xun BaoDepartment of Oncology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Jing LiDepartment of Oncology, School of Medicine, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-9924-1386
Hanaa HaririBiological Sciences Department, Wayne State University, Detroit, MI 48202, USA.

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
Subcellular mechanisms coupling lipid synthesis and methionine metabolismR35GM150892 · NIGMS · WAYNE STATE UNIVERSITY · PI Hanaa Hariri · 2023 to 2026
$1.5M
NCI NIH HHS P30 CA022453NIGMS NIH HHS R35 GM150892NIGMS NIH HHS R35GM150892
6 · The paper itself

Abstract

S-adenosylmethionine (AdoMet) is a central metabolite required for methylation and sulfur metabolism, synthesized in

Indexed as

GlucoseMethionine AdenosyltransferaseSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsS-AdenosylmethionineCytosolGlucoseMethionine AdenosyltransferaseSaccharomyces cerevisiae ProteinsS-Adenosylmethionineenzyme assembliesmetabolic fluxnutrient stressS-adenosylmethionine (AdoMet)

Identifiers

PMID42505377
PMCPMC13406880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.