ArticleInfection and immunity2026
Protein kinase F regulates the virulence of
Flor Torres-Juarez, Shivangi Rastogi, David Young, Ashton T Belew, Paul J Baker, Viplov K Biswas, Shannon E Khan, Najib M El-Sayed, D Branch Moody, Katrin D Mayer-Barber and 1 more
Abstract read
In one paragraphArticle in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
11 authors.
Flor Torres-Juarez *Inflammation and Innate Immunity Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Shivangi Rastogi *Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.ORCID 0000-0002-0046-0045 David YoungDivision of Rheumatology, Immunity and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Ashton T BelewDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.
Paul J BakerInflammation and Innate Immunity Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Viplov K BiswasDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.
Shannon E KhanDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.
Najib M El-SayedDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.ORCID 0000-0001-7970-3312 D Branch MoodyDivision of Rheumatology, Immunity and Inflammation, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Katrin D Mayer-BarberInflammation and Innate Immunity Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.ORCID 0000-0002-0311-3233 Volker BrikenDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.ORCID 0000-0001-5830-6107 Funding
Study of M. tuberculosis under human host selection to identify virulence and barrier lipids (Project 1)U19AI162584 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI WOOD, ROBIN · 2021 to 2025
$13.5MChemical Biological Discovery of Lipid Virulence Factors in the Major Bacterial PathogensR01AI165573 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2022 to 2025
$3.0MManipulation of the host cell inflammasome by Mycobacterium tuberculosisR01AI147630 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI VOLKER BRIKEN · 2021 to 2026
$3.0MNational Institute of Allergy and Infectious Diseases R01AI147630National Institute of Allergy and Infectious Diseases R01 AI165573National Institute of Allergy and Infectious Diseases U19 AI162584NHLBI NIH HHSNIAID NIH HHS R01 AI147630NIAID NIH HHS R01 AI165573NIAID NIH HHS U19 AI162584
6 · The paper itselfAbstract
The serine/threonine protein kinase F (PknF) of
Indexed as
Bacterial ProteinsMycobacterium tuberculosisTuberculosisAnimalsFemaleGene DeletionInflammasomesLipidsLungMacrophagesMiceMice, Inbred C57BLNLR Family, Pyrin Domain-Containing 3 ProteinVirulenceBacterial ProteinsInflammasomesLipidsNLR Family, Pyrin Domain-Containing 3 Proteinphthiocerol dimycocerosateinflammasomePDIMserine/threonine kinasestuberculosisvirulence gene
Identifiers
PMID42505131
PMCPMC13552113
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