Evidence map›Paper›PMID 42504864›Full record

ArticlePediatric pulmonology2026

Comparing Multiple Breath Washout Parameters in a Matched Cohort of Children With Cystic Fibrosis and Primary Ciliary Dyskinesia.

Lise Vanvuchelen, Astrid Vermaut, Marijke Proesmans, François Vermeulen, Mieke Boon

Abstract readComparative Study
In one paragraph

Article in Pediatric pulmonology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lise VanvuchelenDepartment of Development and Regeneration, Woman and Child Unit, Leuven, Belgium.ORCID https://orcid.org/0009-0001-8346-9693
Astrid VermautDepartment of Development and Regeneration, Woman and Child Unit, Leuven, Belgium.ORCID https://orcid.org/0000-0002-4145-491X
Marijke ProesmansDepartment of Development and Regeneration, Woman and Child Unit, Leuven, Belgium.ORCID https://orcid.org/0000-0002-5576-9517
François VermeulenDepartment of Development and Regeneration, Woman and Child Unit, Leuven, Belgium.ORCID https://orcid.org/0000-0003-2303-2470
Mieke BoonDepartment of Development and Regeneration, Woman and Child Unit, Leuven, Belgium.ORCID https://orcid.org/0000-0001-8138-5405

Funding

Koning Boudewijnstichting
6 · The paper itself

Abstract

backgroundCystic Fibrosis (CF) and primary ciliary dyskinesia (PCD) are congenital disorders characterized by impaired mucociliary clearance, resulting in chronic airway infection, inflammation, and progressive lung damage. CF lung disease involves defective CFTR function throughout the entire airway epithelium, whereas PCD originates from dysfunction of motile respiratory cilia located predominantly in proximal airways. Diagnostic tools such as FEV

objectivesTo compare LCI between age and FEV

methodsThis retrospective cross-sectional study included pwCF and pwPCD aged 6-20 years with available MBW and spirometry data (2011-2024).

resultsPwCF (n23, median age 14.4 y) had similar FEV

conclusionDespite similar FEV

Indexed as

Ciliary Motility DisordersCystic FibrosisKartagener SyndromeAdolescentBreath TestsChildCross-Sectional StudiesFemaleForced Expiratory VolumeHumansMaleMucociliary ClearanceRespiratory Function TestsRetrospective StudiesSpirometryYoung Adultcystic fibrosislung clearance indexprimary ciliary dyskinesia

Identifiers

PMID42504864
PMCPMC13403291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.