Evidence map›Paper›PMID 42504800›Full record

ArticleThe Cochrane database of systematic reviews2026

Switching from sulphasalazine or oral 5-aminosalicylic acid to another oral 5-aminosalicylic acid drug in the maintenance of remission in ulcerative colitis.

Osama Abed, Andreas Hallan, Mie Micheelsen Norlén, Lars Koch Hansen, Mette Munk Lauridsen, Maiken Thyregod Jørgensen, Jens Kjeldsen

Abstract read
In one paragraph

Article in The Cochrane database of systematic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Osama AbedDepartment of Gastroenterology, Lillebaelt Hospital, Vejle, Denmark.ORCID https://orcid.org/0009-0007-0957-1378
Andreas HallanMedical Department, Levanger Hospital, Levanger, Norway.ORCID https://orcid.org/0000-0002-8093-078X
Mie Micheelsen NorlénDepartment of Gastroenterology, Lillebaelt Hospital, Vejle, Denmark.ORCID https://orcid.org/0000-0002-8118-2576
Lars Koch HansenDepartment of Gastroenterology, Lillebaelt Hospital, Vejle, Denmark.ORCID https://orcid.org/0000-0003-2699-0041
Mette Munk LauridsenDepartment of Gastroenterology, Esbjerg and Grindsted Hospital, Esbjerg, Denmark.ORCID https://orcid.org/0000-0003-0586-8549
Maiken Thyregod JørgensenDepartment of Gastroenterology, Lillebaelt Hospital, Vejle, Denmark.
Jens KjeldsenDepartment of Medical Gastrointestinal Diseases, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0000-0001-8148-6572

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the probability of failure to maintain clinical remission, endoscopic remission, or both, following a switch from SASP or oral 5-ASA drug (comparator) to another oral 5-ASA drug (experimental) in adult ulcerative colitis patients at 52 weeks of follow-up. The intervention of switching to the experimental drug will be compared to the continuation of the comparator drug. To assess the safety of switching from SASP or oral 5-ASA to another oral 5-ASA drug in the aforementioned population.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalColitis, UlcerativeDrug SubstitutionMesalamineSulfasalazineAdministration, OralHumansMaintenance ChemotherapyRandomized Controlled Trials as TopicRemission InductionResearch DesignSystematic Reviews as TopicAnti-Inflammatory Agents, Non-SteroidalMesalamineSulfasalazine

Identifiers

PMID42504800
PMCPMC13403229

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.