ArticleCureus2026
Pulmonary Cryptococcosis With Suspected Central Nervous System Involvement in a Patient With Sarcoidosis and CD4 Lymphopenia: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Sarcoidosis is a multisystem granulomatous disorder associated with immune dysregulation and impaired cell-mediated immunity, which may increase susceptibility to opportunistic infections, including cryptococcosis. The clinical and radiological overlap between sarcoidosis progression, neurosarcoidosis, and cryptococcal infection can create a significant diagnostic challenge, particularly when neurological symptoms are present. We present a 50-year-old male with a 15-year history of pulmonary sarcoidosis and CD4 lymphopenia who developed pulmonary cryptococcosis with subsequent symptoms concerning for central nervous system (CNS) involvement after self-discontinuation of antifungal therapy. His clinical course was notable for neck stiffness, photophobia, headaches, cognitive slowing, positive serum cryptococcal antigen testing, bronchoscopy confirming
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