ReviewHealth science reports2026
Chronic Diseases and Health Related Quality of Life in South and Southeast Asia: A Systematic Review of Burden, Interventions, and Measurement Tools.
Review in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In South and Southeast Asia, chronic diseases (CD) are a major public health concern and have a considerable impact on people's quality of life (QoL). CD and their ailments place a dual burden of sickness and socioeconomic difficulties on afflicted people and healthcare systems. Aim: This review aims to provide a comprehensive synthesis of evidence on the relationship between chronic diseases and HRQoL in the region, focusing on study populations, disease types, methodologies, sample sizes, and assessment tools used. Methods: A systematic search was conducted to identify studies published between 2014 and 2024 that assessed HRQoL among patients with CD in South and Southeast Asia. Eligible studies included cross-sectional, observational, prospective cohort, and economic evaluation designs involving conditions such as chronic obstructive pulmonary disease (COPD), chronic kidney disease (CKD), diabetes mellitus, sarcopenia, cardiovascular diseases, breast cancer, and hepatitis C. Data extracted included study design, sample size, participant characteristics, and validated HRQoL measurement instruments. Results: Twenty-five studies conducted across multiple South and Southeast Asian countries were included. Sample sizes ranged from 99 to 816 participants. A variety of validated instruments were used to assess HRQoL, including the St. George's Respiratory Questionnaire (SGRQ), Kidney Disease Quality of Life (KDQOL), WHOQOL-BREF, and Short Form-36 (SF-36). Overall, CD were consistently associated with reduced HRQoL, with variations influenced by disease severity, comorbidities, and socioeconomic status. Specific challenges included reduced functional capacity among patients with sarcopenia and significant decisional conflict among patients with CKD. In addition, economic evaluations, particularly for hepatitis C treatments using direct-acting antivirals, highlighted important cost-effectiveness considerations. Conclusion: CD negatively affect HRQoL, which is influenced by disease severity, sociocultural factors, and barriers to healthcare access. Community-based disease management, telemedicine, culturally tailored health education, and financial protection policies may improve outcomes. Future studies should assess the effectiveness and scalability of these interventions across diverse regional settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.