Evidence map›Paper›PMID 42504103›Full record

ArticleBJPsych open2026

Protocol for the MyPREPED trial: hybrid type 2 effectiveness-implementation trial of a peer-delivered digital self-management tool (MyBRANCHES) for young people in Australia transitioning from early intervention in psychosis services.

Alyssa Milton, Ellie Brown, Urska Arnautovska, Priya Vaughan, Caroline Gao, Mary Lou Chatterton, Elizabeth Stratton, Nicola Hancock, Justin Chapman, Ravi Iyer and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJPsych open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Alyssa MiltonFaculty of Medicine and Health, University of Sydney, Australia.ORCID https://orcid.org/0000-0002-4326-0123
Ellie BrownCentre for Youth Mental Health, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Australia.ORCID https://orcid.org/0000-0002-1645-5443
Urska ArnautovskaFaculty of Medicine, The University of Queensland, Australia.ORCID https://orcid.org/0000-0002-7780-8441
Priya VaughanFaculty of Medicine and Health, University of Sydney, Australia.
Caroline GaoCentre for Youth Mental Health, The University of Melbourne, Australia.ORCID https://orcid.org/0000-0002-0987-2759
Mary Lou ChattertonSchool of Public Health and Preventive Medicine, Monash University, Australia.ORCID https://orcid.org/0000-0003-4902-9448
Elizabeth StrattonFaculty of Medicine and Health, University of Sydney, Australia.ORCID https://orcid.org/0000-0003-0699-7588
Nicola HancockSchool of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Australia.
Justin ChapmanMetro South Addiction and Mental Health Services, Metro South Health Service District, Woolloongabba, Australia.
Ravi IyerSwinburne University of Technology, Australia.
Simran SinghFunctional Recovery Team, Uniting NSW ACT, Sydney, Australia.
Saahil MalhotraFunctional Recovery Team, Uniting NSW ACT, Sydney, Australia.
Sam BataraFunctional Recovery Team, Uniting NSW ACT, Sydney, Australia.
Symphony ChakmaFunctional Recovery Team, Uniting NSW ACT, Sydney, Australia.
Deanna De CiccoOrygen, The National Centre of Excellence in Youth Mental Health, University of Melbourne, Australia.
Hadley LindsayFaculty of Medicine and Health, University of Sydney, Australia.
Anthony HarrisFaculty of Medicine and Health, University of Sydney, Australia.
Dan SiskindSchool of Medicine, University of Queensland, Australia.ORCID https://orcid.org/0000-0002-2072-9216
Nicola WarrenFaculty of Medicine, The University of Queensland, Australia.ORCID https://orcid.org/0000-0002-0805-1182
Cate McHughFunctional Recovery Team, Uniting NSW ACT, Sydney, Australia.
Peter McArdleMetro South Addiction and Mental Health Services, Metro South Health Service District, Woolloongabba, Australia.
Darren PhungTechLab, University of Sydney, Australia.
Jim CookTechLab, University of Sydney, Australia.
Andrew ThompsonCentre for Youth Mental Health, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Australia.
Nick GlozierFaculty of Medicine and Health, University of Sydney, Australia.ORCID https://orcid.org/0000-0002-0476-9146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeer-supported self-management at discharge from early intervention in psychosis services (EIPS) has received limited attention. The MyPREPED (My Personal Recovery Plan for Early Discharge) trial will evaluate a co-designed, digital and paper-based, peer-delivered recovery and self-management focused intervention, tailored for young people exiting EIPS.

aimsThis protocol describes a hybrid type 2 effectiveness-implementation trial designed to assess MyPREPED's impact, feasibility, real-world implementation and cost-utility.

methodThis multi-site, mixed-method, two-arm (1:1), parallel-group, randomised controlled trial (MyPREPED versus treatment as usual) trial will be delivered across eight Australian EIPS that deliver ultra-high risk and/or first-episode psychosis streams, using a hybrid type 2 implementation-effectiveness design. Eligible participants are young people aged 16 years and over within 6 months of planned discharge from EIPS. Peer coaches will deliver up to ten sessions of using a self-management plan (modules: discharge, recovery, well-being, relapse prevention, goal-setting, service navigation). Co-primary outcomes include (a) mental health recovery (Recovery Assessment Scale - Domains and Stages; effectiveness outcome) and (b) feasibility (Feasibility of Implementation Measure; implementation outcome). Secondary outcomes assess broader effectiveness domains (mental health quality of life, clinical and functional outcomes) and other implementation outcomes. A cost-utility analysis will estimate incremental costs and quality-adjusted life-years associated with MyPREPED, alongside a secondary cost-effectiveness analysis. Analyses will follow intention-to-treat principles, using mixed-effects models.

conclusionsThis study will provide the first rigorous test of a co-designed, peer-delivered recovery and self-management focused intervention specifically targeting EIPS discharge.

Indexed as

digital mental healthdischargeEarly psychosispeer supportself-management

Identifiers

PMID42504103
PMCPMC13419609

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.