Evidence map›Paper›PMID 42503914›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2026

[Advancement in the role of exosomes for hepatitis B virus infection diagnosis and treatment: mechanisms and clinical applications].

M X Du, W T Hua, S H Wan, Y T Gao, Y L Zhang, J Y Liu, X Zhang

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M X DuDepartment of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an 710032, China Department of Basic Medical Sciences, Air Force Medical University, Xi'an 710032, China.
W T HuaDepartment of Basic Medical Sciences, Air Force Medical University, Xi'an 710032, China.
S H WanDepartment of Basic Medical Sciences, Air Force Medical University, Xi'an 710032, China.
Y T GaoDepartment of Basic Medical Sciences, Air Force Medical University, Xi'an 710032, China.
Y L ZhangDepartment of Basic Medical Sciences, Air Force Medical University, Xi'an 710032, China.
J Y LiuDepartment of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an 710032, China.
X ZhangDepartment of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an 710032, China.

Funding

National Natural Science Foundation of China 81903145, 81972026
6 · The paper itself

Abstract

Hepatitis B virus (HBV) infection is a major global public health problem, causing approximately one million deaths annually. Exosomes are nanosized vesicles (30-150 nm) enclosed in a lipid bilayer membrane, secreted by almost all cells, and carry bioactive substances such as proteins, nucleic acids, and lipids, thereby playing a key role in intercellular communication. Recent research results have shown that exosomes play an important advanced role in the diagnosis and treatment of HBV infection. This review systematically summarizes the dual role of exosomes in HBV infection (promoting viral transmission and participating in immune regulation), their application as novel biomarkers in the diagnosis of HBV-related liver diseases, the latest research progress in exosome-based therapeutic strategies, and their current status in clinical translation, with the aim of providing updated and more precise biological markers and therapeutic targets for clinical diagnosis and treatment and offering perspectives for future research directions.

Indexed as

ExosomesHepatitis BBiomarkersHepatitis B virusHumansBiomarkers

Identifiers

PMID42503914
PMCPMC13416776

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.