Evidence map›Paper›PMID 42503587›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

The Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale in frontotemporal dementia and Alzheimer's disease.

Jessica Jiang, Eva K Larsen, Benjamin A Levett, Lucy B Core, Sophie A Froud, Ciro Della Monica, Hana Hassanin, Giuseppe Atzori, Chris Jd Hardy, Marc A Busche and 5 more

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In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jessica JiangDementia Research Centre, Queen Square Institute of Neurology, University College London, London, England, UK.
Eva K LarsenDementia Research Centre, Queen Square Institute of Neurology, University College London, London, England, UK.
Benjamin A LevettDementia Research Centre, Queen Square Institute of Neurology, University College London, London, England, UK.
Lucy B CoreDementia Research Centre, Queen Square Institute of Neurology, University College London, London, England, UK.
Sophie A FroudDementia Research Centre, Queen Square Institute of Neurology, University College London, London, England, UK.
Ciro Della MonicaSurrey Sleep Research Centre, University of Surrey, Guildford, England, UK.
Hana HassaninUK DRI Care Research and Technology Centre, Imperial College London and University of Surrey, Guildford, England, UK.
Giuseppe AtzoriSurrey Sleep Research Centre, University of Surrey, Guildford, England, UK.
Chris Jd HardyDementia Research Centre, Queen Square Institute of Neurology, University College London, London, England, UK.
Marc A BuscheUK Dementia Research Institute, University College London, London, UK.
Derk-Jan DijkSurrey Sleep Research Centre, University of Surrey, Guildford, England, UK.
Victoria L RevellSurrey Sleep Research Centre, University of Surrey, Guildford, England, UK.
Samuel S HarrisUK Dementia Research Institute, University College London, London, UK.
Sofia H ErikssonDepartment of Clinical and Experimental Epilepsy, National Hospital for Neurology and Neurosurgery, London, England, UK.
Jason D WarrenDementia Research Centre, Queen Square Institute of Neurology, University College London, London, England, UK.

Funding

Alzheimer's Association 25AARG-1376792Alzheimer's Association AARF-23-1149637Alzheimer's Society 627Alzheimer's Society AS-PG-16-007Brain Research Trust,BrightFocus Foundation A2019112Sby Alzheimer's Research UKCure Alzheimer's FundNational Brain AppealNational Institute for Health and Care Research NIHR204280National Institute for Health and Care Research NIHR306146Royal National Institute for Deaf People G105 to J.D.W.The Wolfson FoundationUCL Research Excellence ScholarshipUK Dementia Research Institute UKDRI-1208 to M.A.B.UK Dementia Research Institute UKDRI-7206 to D.J.D.UK Medical Research CouncilUK Research and Innovation Future Leaders Fellowship (MR/X011038/1)University College LondonWolfson Foundation
6 · The paper itself

Abstract

introductionSleep disturbance is common in dementia, impacting daytime function and care. Compared with Alzheimer's disease (AD), sleep in frontotemporal dementia (FTD) is poorly characterized.

methodsWe assessed sleep using the Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index in 58 people with primary progressive aphasia (PPA) and right temporal variant FTD, 32 with AD, and 36 cognitively healthy older volunteers. All participants had cognitive and behavioral assessments. Groups were compared using non-parametric statistics and correlations assessed sleep versus other indices.

resultsSubjective sleep duration was increased in all syndromic groups. AD and semantic PPA were associated with increased daytime somnolence. Reported sleep quality varied between syndromes. Across the disease cohort, somnolence correlated with behavioral and empathy deficits; in AD, poorer sleep quality correlated additionally with self-monitoring deficits. DISCUSSION: FTD and AD syndromes have distinct sleep phenotypes, and sleep alterations are associated with behavior. Standard sleep scales require careful interpretation in dementia.

Indexed as

Alzheimer DiseaseFrontotemporal DementiaSleepinessSleep QualitySleep Wake DisordersAgedAphasia, Primary ProgressiveFemaleHumansMaleMiddle AgedNeuropsychological TestsSleep Durationalzheimer's diseaseepworth sleepiness scalefrontotemporal dementiapittsburgh sleep quality indexprimary progressive aphasiasleep

Identifiers

PMID42503587
PMCPMC13402253

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.