ArticleJournal of applied clinical medical physics2026
A geometry-based scaling model for stereotactic treatment volume definition in stereotactic centralized ablative radiation therapy.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStereotactic Centralized Ablative Radiation Therapy (SCART) is a spatially fractionated radiotherapy strategy designed for large or bulky tumors by delivering an intensified ablative dose to a centrally located subvolume while allowing controlled dose reduction toward the tumor periphery. However, clinical implementation of SCART critically depends on reproducible definition of the stereotactic treatment volume (STV), which currently lacks a standardized geometric framework. PURPOSE: To develop and preliminarily evaluate a geometry-based scaling model for STV definition based on internal dose fall-off characteristics under stereotactic volumetric modulated arc therapy (VMAT) delivery.
methodsA phantom-based stereotactic VMAT planning study was performed using idealized cylindrical STVs with radii of 1-3 cm and axial lengths of 3-10 cm. VMAT plans were generated using prescription doses of 15-24 Gy per fraction over three fractions. Internal dose fall-off was quantified using the equivalent radius (r
resultsThe extracted 15 Gy isodose surface demonstrated reproducible geometry-associated attenuation behavior across the investigated stereotactic VMAT configurations. The equivalent radius (r
conclusionThis study establishes a geometry-based STV scaling framework for SCART based on reproducible internal dose fall-off characteristics under stereotactic VMAT delivery. The proposed dose-specific regression model provides a practical and physically interpretable approach for inward STV scaling from measurable gross tumor volume geometry and may support more reproducible implementation of SCART planning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.