Evidence map›Paper›PMID 42503219›Full record

ArticleChemistry & biodiversity2026

Antioxidant and Cytotoxic Potential of an Undescribed Lignan Isolated From the Pooled Stem and Leaf Extract of Conocarpus lancifolius.

Muhammad Khurm, Saisai Xin, Asmat Ullah, Majid Manzoor, Muhammad Umer Ghori, Xin Liu, JingJing Zhao, Rabia Ahmad Abbasi, Hui Zhang, Guanqun Zhan and 2 more

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Muhammad KhurmSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.ORCID https://orcid.org/0000-0002-3085-2808
Saisai XinSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Asmat UllahCollege of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China.ORCID https://orcid.org/0000-0002-6572-1242
Majid ManzoorInstitute of Drug Discovery Technology, Ningbo University, Ningbo, China.
Muhammad Umer GhoriDepartment of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
Xin LiuSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
JingJing ZhaoSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Rabia Ahmad AbbasiSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Hui ZhangSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Guanqun ZhanSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Xinxin ZhangSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Zengjun GuoSchool of Pharmacy, Xi'an Jiaotong University, Xi'an, China.

Funding

Key R&D Plan of Shaanxi Province, China 2024SF-ZDCYL-03-18Qin Chuangyuan Scientists and Engineers Team Construction Program of Shaanxi Province 2022KXJ-131Traditional Chinese Medicine Research of the Shaanxi Provincial Administration of Traditional Chinese Medicine SZY-KJCYC-2025-JC-046
6 · The paper itself

Abstract

A previously unknown lignan, methyl-(7S, 8S)-4-hydroxy-4',7-epoxy-8,3'-neolignan-7'-ate (MEHN), was isolated from an extract prepared from the pooled stems and leaves of Conocarpus lancifolius and structurally elucidated using comprehensive spectroscopic analysis and ECD calculations. The compound revealed prominent antiradical activity in both ABTS (IC

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsLignansPlant ExtractsTracheophytaBenzothiazolesBiphenyl CompoundsCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansMolecular StructurePicratesPlant LeavesAntineoplastic Agents, PhytogenicAntioxidantsBenzothiazolesBiphenyl CompoundsLignansPicratesPlant ExtractsSulfonic Acidsantioxidant activityConocarpus lancifoliuscytotoxic potentialdrug‐likeness analysislignanstructural characterization

Identifiers

PMID42503219
PMCPMC13401968

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.