Evidence map›Paper›PMID 42503196›Full record

ArticleChemistry & biodiversity2026

Chemical Composition and Biological Activities of Propolis From Eastern Anatolia: Antioxidant, Enzyme Inhibitory, and Antimicrobial Activities.

Mehmet Çağlar Fırat, Zeynep Akşit, Samed Şimşek, Sevgi Altın, İlyas Yıldız, Hüseyin Akşit

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mehmet Çağlar FıratDepartment of Hotel, Restaurant and Service, Tourism and Hospitality Vocational School, Erzincan Binali Yıldırım University, Erzincan, Türkiye.ORCID https://orcid.org/0000-0003-4920-4920
Zeynep AkşitDepartment of Hotel, Restaurant and Service, Tourism and Hospitality Vocational School, Erzincan Binali Yıldırım University, Erzincan, Türkiye.
Samed ŞimşekDepartment of Medical Services and Techniques, Çayırlı Vocational School, Erzincan Binali Yıldırım University, Erzincan, Türkiye.ORCID https://orcid.org/0000-0001-8451-3425
Sevgi AltınInstitute of Science and Technology, Erzincan Binali Yıldırım University, Erzincan, Türkiye.ORCID https://orcid.org/0000-0002-0820-912X
İlyas YıldızDepartment of Molecular Biology and Genetics, Faculty of Arts and Science, Gaziosmanpaşa University, Tokat, Türkiye.
Hüseyin AkşitDepartment of Analytical Chemistry, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Propolis is recognized for its biological activities; however, its chemical composition varies according to environmental conditions, which presents challenges for quality standardization and biological evaluation. Although propolis has been widely investigated, information regarding variation among samples collected from geographically close locations within the same region is limited. Therefore, this study investigated whether propolis samples obtained from different locations within Erzincan Province exhibit differences in chemical composition and biological activities and evaluated the relationship between environmental conditions and propolis characteristics. Eleven propolis samples collected from Erzincan, Türkiye, were analyzed for phenolic composition, antioxidant capacity, antimicrobial activity, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glucosidase inhibitory activities. Twenty-eight compounds were identified, with gallic acid, protocatechuic acid, chlorogenic acid, hydroxybenzaldehyde, caffeic acid, and vanillin detected as major constituents. AChE inhibitory activity varied between 1.28 and 6.44 µg/mL, while BChE inhibitory activity varied between 1.85 and 9.66 µg/mL. All samples exhibited antibacterial activity. Total phenolic and flavonoid contents were 141.70-255.04 mg GAE/g extract and 30.48-93.81 mg QE/g extract, respectively. The KMH sample showed the antioxidant activity. The results demonstrated variation in phytochemical composition and biological activities among propolis samples collected within the same province, indicating associations between flora, environmental conditions, propolis quality, and bioactivity.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAntioxidantsCholinesterase InhibitorsGlycoside Hydrolase InhibitorsPropolisAcetylcholinesterasealpha-GlucosidasesBiphenyl CompoundsButyrylcholinesteraseMicrobial Sensitivity TestsPhenolsPicratesTurkeyAcetylcholinesterasealpha-GlucosidasesAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsBiphenyl CompoundsButyrylcholinesteraseCholinesterase InhibitorsGlycoside Hydrolase InhibitorsPhenolsPicratesPropolisantimicrobial activityantioxidant activitybioactive compoundschemical compositionenzyme inhibitionpropolis

Identifiers

PMID42503196
PMCPMC13401962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.