Evidence map›Paper›PMID 42502781›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Cochlear implants are associated with reduced cognitive decline risk: A 20-year cohort study.

Filippos Anagnostakis, Michail Kokkorakis, Ilias Papadimopoulos, Junhao Wen, Christos Davatzikos

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Filippos AnagnostakisArtificial Intelligence in Biomedical Imaging Laboratory (AIBIL), Center for AI and Data Science for Integrated Diagnostics (AI2D), Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.ORCID https://orcid.org/0000-0001-7374-8798
Michail KokkorakisDepartment of Internal Medicine Yale School of Medicine New Haven Connecticut USA.
Ilias PapadimopoulosAlma Mater Studiorum-Medicine and Surgery University of Bologna Bologna Italy.
Junhao WenLaboratory of AI and Biomedical Science (LABS) Columbia University New York New York USA.
Christos DavatzikosArtificial Intelligence in Biomedical Imaging Laboratory (AIBIL), Center for AI and Data Science for Integrated Diagnostics (AI2D), Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.

Funding

Machine Learning and Large-scale Imaging analytics for dimensional representations of brain trajectories in aging and preclinical Alzheimer's Disease: The brain aging chart and the iSTAGING consortiumRF1AG054409 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2023
$6.3M
NIA NIH HHS RF1 AG054409
6 · The paper itself

Abstract

Introduction: We investigated the association between cochlear implantation and the risk of cognitive decline in adults with hearing loss using a national population cohort. Methods: Our cohort comprised 4106 participants who underwent cochlear implantation and matched controls with untreated hearing loss, followed over a median of 7.3 years. Propensity score matching was applied to control for confounders, and Kaplan-Meier analysis was used to assess time-to-event outcomes. Results: Participants with cochlear implants had a significantly reduced risk of all-cause dementia (hazard ratio [HR] 0.61, 95% confidence interval [CI] 0.50-0.74), mild cognitive impairment (HR 0.53, 95% CI 0.40-0.70), and memory loss (HR 0.54, 95% CI 0.45-0.65) compared with controls. These associations remained significant in sex-stratified analyses for both male and female participants. Discussion: These results support early auditory intervention as a dementia prevention strategy and warrant further research with longer follow-up periods across diverse populations.

Indexed as

cochlear implantsdementiaepidemiologyhearing lossMCImemory loss

Identifiers

PMID42502781
PMCPMC13400825

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.