Evidence map›Paper›PMID 42502635›Full record

ReviewJournal of the Pediatric Orthopaedic Society of North America2026

Patellofemoral Instability in Children with Down Syndrome.

Robert G Yoder, Paraskevi M Limberatos, Joseph A Magoline, Melanie A Morscher, Patrick M Riley, Kenneth T Bono, John D Polousky, Robert G Tysklind

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of the Pediatric Orthopaedic Society of North America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert G YoderDepartment of Orthopaedic Surgery, Cleveland Clinic Akron General, Akron, OH, USA.
Paraskevi M LimberatosDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Joseph A MagolineDepartment of Orthopedics, Akron Children's Hospital, Akron, OH, USA.
Melanie A MorscherDepartment of Orthopedics, Akron Children's Hospital, Akron, OH, USA.
Patrick M RileyDepartment of Orthopedics, Akron Children's Hospital, Akron, OH, USA.
Kenneth T BonoDepartment of Orthopedics, Akron Children's Hospital, Akron, OH, USA.
John D PolouskyDepartment of Orthopedics, Akron Children's Hospital, Akron, OH, USA.
Robert G TysklindDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of patellofemoral instability (PFI) in patients with Down syndrome (DS) is 10% to 20%. Treatment of PFI in this cohort has evolved over the past four decades. Nonoperative management largely prevails today; however symptomatic patients with DS and recurrent instability may benefit from patellar stabilization surgery. Combined, physeal-sparing soft tissue procedures have become the focus of modern-day surgeons when operative intervention is pursued in skeletally immature patients. This review article outlines the seldom-discussed topic of PFI in patients with DS and highlights the need for high-quality, outcome-based research on the optimal management in this specific cohort. Key Concepts: (1)Asymptomatic patients with Down syndrome (DS) and patellofemoral instability (PFI) are treated nonoperatively.(2)Surgical treatment of PFI has evolved and may benefit patients with DS and symptomatic PFI.(3)Approximately 20% of patients with DS develop PFI. Reported recurrence rates following surgical intervention range from 0% to 20%.(4)High-quality, outcome-based research in this population is needed.

Indexed as

Down syndromePatellofemoral instabilityPediatric orthopaedics

Identifiers

PMID42502635
PMCPMC13400391

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.