Evidence map›Paper›PMID 42502514›Full record

ArticleCureus2026

Paraneoplastic Opsoclonus Without Myoclonus Secondary to High-Grade Serous Carcinoma in an Adult.

Caleb Bowman, Ibrahim Mustafa

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Caleb BowmanMedicine, Carle Illinois College of Medicine, Urbana, USA.
Ibrahim MustafaNeurology, Carle Illinois College of Medicine, Urbana, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opsoclonus is a rare disorder characterized by chaotic, multidirectional eye movements and most commonly presents as part of the opsoclonus-myoclonus syndrome (OMS). Although typically described in pediatric populations, particularly in association with neuroblastoma, adult presentations are exceptionally rare and are most often paraneoplastic or infectious in origin. We describe the case of a woman in her 60s who developed isolated opsoclonus associated with a newly diagnosed poorly differentiated metastatic high-grade serous carcinoma. The clinical course, diagnostic evaluation, antibody profiling, and immunomodulatory treatments, including intravenous immunoglobulin (IVIG), corticosteroids, and plasmapheresis, are reviewed. This case highlights the diagnostic challenges and therapeutic considerations associated with adult-onset paraneoplastic opsoclonus.

Indexed as

immunotherapyopsoclonusopsoclonus-myoclonus syndromeparaneoplastic syndromeserous carcinoma

Identifiers

PMID42502514
PMCPMC13401244

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.