ReviewBiomaterial investigations in dentistry2026
Protease-processed amnion: biological rationale and translational constraints.
Review in Biomaterial investigations in dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Amnion-derived biomaterials have attracted interest in dentistry because of their anti-inflammatory, anti-scarring, and wound-healing properties. Among available preparation strategies, protease-processed amnion has been proposed as a method to better preserve structural integrity and support cellular responses, with preliminary evidence suggesting accelerated wound healing. This mini review examines the biological rationale for protease-processed amnion, compares it with conventional membrane processing approaches, and evaluates its possible role in extraction socket healing, periodontal regeneration, and oroantral repair. Available evidence suggests promising preclinical performance, but clinical support in intraoral settings remains limited. Key barriers include variability in processing, sterilization, storage, regulatory oversight, and the need for well-designed clinical trials before routine dental use can be recommended.
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