Evidence map›Paper›PMID 42502472›Full record

ArticleNeuroimage. Reports2026

Multi-compartment Myelin Streamline Decomposition reveals tract-specific and global brain network myelination in Multiple Sclerosis.

Antonia L Wenger, Sara Bosticardo, Sabine Schaedelin, Alessandro Cagol, Matthias Weigel, Mario Ocampo-Pineda, Po-Jui Lu, Xinjie Chen, Pasquale Calabrese, Jens Kuhle and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroimage. Reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Antonia L WengerTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Sara BosticardoTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Sabine SchaedelinTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Alessandro CagolTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Matthias WeigelTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Mario Ocampo-PinedaTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Po-Jui LuTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Xinjie ChenTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Pasquale CalabreseInterdisciplinary Platform, Psychiatry and Psychology, Division of Molecular and Cognitive Neuroscience, Neuropsychology and Behavioral Neurology Unit, University of Basel, Basel, Switzerland.
Jens KuhleResearch Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.
Ludwig KapposTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Alessandro DaducciDiffusion Imaging and Connectivity Estimation (DICE) Lab, Department of Computer Science, University of Verona, Verona, Italy.
Cristina GranzieraTranslational Imaging in Neurology (ThINk), Department of Biomedical Engineering, Faculty of Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple Sclerosis (MS) disrupts white matter (WM) tract organization, affecting brain networks and neurological function. Current methods lack the capacity to directly quantify tract- and network specific myelin-sensitive measures with clinical outcomes. This cross-sectional study (122 MS patients, 72 females, median age 48.5 years, median EDSS 3.0) applied

Indexed as

Cingulum bundleCorticospinal tractMultiple sclerosismyelin-sensitive measuresNetwork propertiesPhysical disability

Identifiers

PMID42502472
PMCPMC13400364

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.