Evidence map›Paper›PMID 42502404›Full record

ArticleiScience2026

5-hydroxymethylcytosine deposition mediates Polycomb repressive complex 2 function in

Mohansrinivas Chennakesavalu, Gabriel L Lopez, Varsha Gupta, Kelley Moore, Yuqing Xue, Adam Handen, Josie Majowka, Sahil Veeravalli, Ryan Borchert, Monica Pomaville and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Mohansrinivas ChennakesavaluDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Gabriel L LopezDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Varsha GuptaDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Kelley MooreDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Yuqing XueDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Adam HandenDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Josie MajowkaDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Sahil VeeravalliDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Ryan BorchertDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Monica PomavilleDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Alexandre ChlenskiDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Chuan HeDepartment of Chemistry, University of Chicago, Chicago, IL, USA.
Andrea PiuntiDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.
Mark A ApplebaumDivision of Hematology-Oncology, Department of Pediatrics, University of Chicago, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

5-hmCdecitabineH3K27me3MCYN-amplificationneuroblastomaPRC2tazemetostat

Identifiers

PMID42502404
PMCPMC13401028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.