Optic canal decompression in severe therapy refractory optic neuritis: a case report.

Armin Handzic, Pia Niederau, Caroline Seebauer, Christian P Kamm, Oliver Job

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Article in American journal of ophthalmology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Armin HandzicUniversity of Lucerne, Cantonal Hospital of Lucerne, Department of Ophthalmology, Lucerne, Switzerland.

Pia NiederauUniversity of Lucerne, Cantonal Hospital of Lucerne, Department of Neuroradiology, Lucerne, Switzerland.

Caroline SeebauerUniversity of Lucerne, Cantonal Hospital of Lucerne, Department of Otorhinolaryngology Head and Neck Surgery, Lucerne, Switzerland.

Christian P KammUniversity of Lucerne, Cantonal Hospital of Lucerne, Department of Neurology, Lucerne, Switzerland.

Oliver JobUniversity of Lucerne, Cantonal Hospital of Lucerne, Department of Ophthalmology, Lucerne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To describe a unique case of successful optic canal decompression in radiologically confirmed severe optic neuritis involving the optic canal. Observations: A 24-year-old woman experienced severe visual loss in the right eye due to retrobulbar optic neuritis (ON), as an initial symptom of multiple sclerosis. High-dose corticosteroids and subsequent plasmapheresis yielded no improvement. Thus, visual prognosis was considered poor. Since MRI demonstrated ON within the optic canal with only minimal contrast enhancement, findings were compatible with a canalicular compartment syndrome. As a result, an unconventional treatment approach with optic canal decompression (OCD) was pursued. Immediately after the intervention, the patient noticed improved color vision and continued visual improvement, with vision almost restored to 20/30 one month after the intervention. Conclusions and Importance: This case report demonstrates that OCD can be performed safely in severe ON and that it might represent a valuable treatment option in selected cases of ON.

Indexed as

Canalicular compartment syndromeCase reportMultiple sclerosisOptic canal decompressionOptic neuritis

Identifiers

PMID42502363

DOI10.1016/j.ajoc.2026.102626

PMCPMC13400445

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