ArticleClinical, cosmetic and investigational dermatology2026
Central Precocious Puberty and Sjogren-Larsson Syndrome in a Child: A Rare Case Report.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Extremely rare cases show co-occurrence of Sjogren-Larsson syndrome (SLS) and central precocious puberty (CPP), and our understanding of it is still limited. In this case report, we reported a 9-year-old boy (weight: 20 kg; height: 120 cm) showing SLS and CPP simultaneously. The patient presented to our hospital with testicle enlargement and presence of pubic hair. SLS was diagnosed based on the presence of ichthyosis and intelligent disability, together with genetic confirmation by next-generation sequencing, which identified two pathogenic variants (
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