Evidence map›Paper›PMID 42502273›Full record

ArticleBiochemistry and biophysics reports2026

12(S)-HETE regulates the expression of IL-6 and IL-10 in cardiomyocytes through two distinct receptors, TXA2R and BLT2.

Shota Mori, Yuma Takeda, Masashi Tomimatsu, Yusuke Kametani, Naokazu Yoneda, Kaho Egawa, Hiroaki Hase, Shota Tanaka, Masahiro Okuda, Yoshiaki Okada and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shota MoriLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Yuma TakedaLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Masashi TomimatsuLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Yusuke KametaniLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Naokazu YonedaLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Kaho EgawaLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Hiroaki HaseLaboratory of Stem Cell Regeneration and Adaptation, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Shota TanakaLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Masahiro OkudaDepartment of Pharmacy, The University of Osaka Hospital, Suita City, Osaka, Japan.
Yoshiaki OkadaLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Masanori ObanaLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.
Yasushi FujioLaboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita City, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac inflammation contributes to the development and progression of heart failure (HF). Although cytokines are key mediators of cardiac inflammation, lipid-derived metabolites also play essential roles; however, their underlying mechanisms remain largely unexplored. Among these metabolites, 12 S-hydroxy-5

Indexed as

12(S)-HETEBLT2CardiomyocyteInflammationLipid mediatorTXA2R

Identifiers

PMID42502273
PMCPMC13400414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.