Evidence map›Paper›PMID 42502110›Full record

ArticleWorld journal of urology2026

The learning curve of waterjet ablation of the prostate: a cumulative sum analysis of surgical and functional outcomes.

Federica Passarelli, Giorgio Graps, Ludovico Maria Basadonna, Fabrizio Longo, Elisa De Lorenzis, Giancarlo Albo, Emanuele Montanari, Luca Boeri

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Federica PassarelliDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giorgio GrapsDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Ludovico Maria BasadonnaDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Fabrizio LongoDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Elisa De LorenzisDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giancarlo AlboDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Emanuele MontanariDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Luca BoeriDepartment of Urology, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. dr.lucaboeri@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAquablation is a semi-automated, ejaculation-sparing surgical option for treatment of benign prostatic hyperplasia (BPH). While previous studies have demonstrated that approximately 50 cases are required to achieve surgical competence in prostate laser enucleation, objective evaluations of Aquablation learning curve remain limited. The aim of this study was to assess Aquablation learning curve using cumulative sum (CUSUM) method, based on operative parameters and postoperative outcomes.

methodsWe retrospectively analyzed data from 80 patients who underwent Aquablation by a single surgeon with prior experience in prostate resection and enucleation (01/2024 - 07/2025). Patient demographics, including prostate volume (PV) and comorbidities, were recorded. Operative parameters were collected. Patient evaluations were conducted at baseline, 3, 6 months postoperatively, including uroflowmetry and assessment using the International Prostate Symptom Score (IPSS). Ejaculation preservation was assessed. Trifecta was defined as preserved ejaculation, IPSS < 8, and maximum urinary flow rate (Qmax) > 15 mL/s at 6 months. Descriptive statistics, linear regression analyses, and CUSUM method were applied.

resultsMedian (interquartile range [IQR]) prostate volume and baseline IPSS-total score were 60 (45-78) mL and 21 (14-27). Median total operative time was 39 (31-47) minutes. Postoperative complications occurred in 18 patients (22.5%). Median IPSS-total score and Qmax improved significantly at 3- and 6-month follow-up visits (p < 0.01). Antegrade ejaculation was preserved in 81.2% of patients at 6-month follow-up. Trifecta at 6 months was achieved in 49 patients (61.2%). CUSUM analysis demonstrated that learning curve for setup and ablation tissue time reached plateau after 14 cases, while coagulation time stabilized after 21 procedures. CUSUM charts for trifecta achievement revealed an initial learning phase requiring 18 cases to achieve stable performance, subsequently maintained.

conclusionAquablation is a reproducible, ejaculation-sparing surgical option for BPH, with procedural efficiency and stable functional outcomes achieved after approximately 12-21 cases. Aquablation offers a faster acquisition of technical proficiency due to its high degree of automation and standardized planning, leading to a rapid integration into clinical practice.

Indexed as

AquablationLearning CurveProstatectomyProstatic HyperplasiaAgedEjaculationHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeEjaculationLearning curveLower urinary tract symptomsMinimally invasive surgical techniquesProstateWaterjet ablation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.